Clinical trialNCT03910075CompletedPhase 3Interventional

Perinatal Arterial Stroke: A Multi-site RCT of Intensive Infant Rehabilitation (I-ACQUIRE)

SponsorVirginia Polytechnic Institute and State UniversityEnrollment216HemiparesisPerinatal Stroke

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a Phase III clinical trial to compare the efficacy of two dosages of a new infant rehabilitation protocol - I-ACQUIRE - to usual and customary forms of infant rehabilitation in infants who experienced Perinatal Arterial Stroke (PAS).

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Sharon L Ramey, Ph.D.
Virginia Polytechnic Institute and State University
Principal Investigator
clinicaltrials.gov ↗
Warren Lo, M.D.
Children's National Research Institute
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

15 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Uscd Health la Jolla
La Jolla, California, United States
Yale New Haven Children'S Hospital
New Haven, Connecticut, United States
Ann & Robert H. Lurie Children'S Hospital of Chicago
Chicago, Illinois, United States
Kennedy Krieger Institute - Fairmount Rehabilitation
Baltimore, Maryland, United States
Boston Children'S Hospital
Boston, Massachusetts, United States
C.S. Mott Children'S Hospital
Ann Arbor, Michigan, United States
Washington University School of Medicine, St. Louis Children'S Hospital
St Louis, Missouri, United States
Cincinnati Children'S Hospital Medical Center
Cincinnati, Ohio, United States
Martha Morehouse Medical Plaza
Columbus, Ohio, United States
Children'S Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
the Medical University of South Carolina (musc)
Charleston, South Carolina, United States
Scottish Rite for Children - Dallas
Dallas, Texas, United States
Memorial Hermann Texas Medical Center
Houston, Texas, United States
Fralin Biomedical Research Institute at Virginia Tech
Roanoke, Virginia, United States
University of Wisconsin School of Medicine and Public Health
Madison, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 10 Oct 2019
Primary completion: 16 Jul 2025
Completion: 31 Jul 2025
Last update posted: 1 Jun 2026
Registered enrollment: 216
Registry id: NCT03910075

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.