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Clinical trialNCT03929666CompletedPhase 2Interventional

A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer

SponsorJazz PharmaceuticalsEnrollment74HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

23 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • the Ottawa Hospital Cancer Centre

    Ottawa, Ontario, Canada

  • Princess Margaret Cancer Center

    Toronto, Ontario, Canada

Chile
  • Cecim Biocinetic

    Santiago, Chile

  • Centro Internacional de Estudios Clínicos

    Santiago, Chile

  • Centro de Investigacion Clinica Saga

    Santiago, Chile

  • Icegclinic Research & Care

    Santiago, Chile

South Korea
  • Seoul National University Bundang Hospital

    Seongnam-si, Gyeonggi-do, South Korea

  • Pusan National University

    Busan, South Korea

  • Asan Medical Center

    Seoul, South Korea

  • Korea University Anam Hospital

    Seoul, South Korea

  • Seoul National University Hospital

    Seoul, South Korea

  • Severance Hospital

    Seoul, South Korea

United States
  • Usc/norris Comprehensive Cancer Center

    Los Angeles, California, United States

  • Hoag Memorial Hospital Presbyterian

    Newport Beach, California, United States

  • H. Lee Moffitt Cancer Center

    Tampa, Florida, United States

  • University of Chicago

    Chicago, Illinois, United States

  • the Cancer and Hematology Centers

    Grand Rapids, Michigan, United States

  • Nebraska Methodist Hospital

    Omaha, Nebraska, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, United States

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, United States

  • Sarah Cannon Research Institute

    Nashville, Tennessee, United States

  • Md Anderson Cancer Center

    Houston, Texas, United States

  • Virginia Mason Medical Center

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
29 Aug 2019
Primary completion
30 Aug 2025
Completion
30 Aug 2025
Last update posted
12 Sept 2025
Registered enrollment
74
Registry id
NCT03929666

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.