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Clinical trialNCT03935555TerminatedPhase 1Interventional

Assess the Safety, Tolerability Oral PU-H71 in Subjects Taking Ruxolitinib

SponsorSamus Therapeutics, Inc.Enrollment11Post-Essential Thrombocythemia Myelofibrosis (Post-ET MF)Post-Polycythemia Vera Myelofibrosis (Post-PV MF)Primary Myelofibrosis (PMF)
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a multicenter, Phase 1b study with dose escalation and expansion cohorts designed to assess the safety, tolerability, PK, and preliminary efficacy of PU-H71 in subjects with PMF, Post-PV MF, Post-ET MF, taking stable doses of ruxolitinib.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

3 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Marin Cancer Care - Greenbrae (california Cancer Care A Medical Group, Inc. - Greenbrae)

    Larkspur, California, United States

  • Ronald Reagan Ucla Medical Center

    Los Angeles, California, United States

  • Md Anderson

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PU-H71
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
12 Aug 2019
Primary completion
19 Oct 2022
Completion
4 Nov 2022
Last update posted
17 Nov 2022
Registered enrollment
11
Registry id
NCT03935555

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 11 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.