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Clinical trialNCT03943238RecruitingPhase 1Interventional

TLI, TBI, ATG & Hematopoietic Stem Cell Transplantation and Recipient T Regs Therapy in Living Donor Kidney Transplantation

SponsorStanford UniversityEnrollment22Living Donor Kidney Transplantation
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study will determine whether a preparatory regimen including total lymphoid irradiation (TLI), total body irradiation (TBI), anti-thymocyte globulin (ATG) and infusion of the donor hematopoietic stem cells when given along with recipient regulatory T cells (Tregs) will allow for eventual discontinuation of anti-rejection drugs after living donor kidney transplantation.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

2 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Stanford University

    Palo Alto, California, United States

    Colin Lenihan, MDEverett Meyer, MDJohn Scandling, MDKent Jensen, PhDRichard Hoppe, MDRobert Lowsky, MDStephan Busque, MDThomas Pham, MD
    Recruiting
  • Nothwestern University

    Chicago, Illinois, United States

    James Mathew, PhDJayesh Mehta, MDJoseph Leventhal, MDLorenzo Gallon, MD
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Infusion of Donor Hematopoetic Stem Cells and Recipient Tregs
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
1 Feb 2020
Primary completion
1 Nov 2029
Completion
1 Dec 2029
Last update posted
1 Jul 2026
Registered enrollment
22
Registry id
NCT03943238

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.