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Clinical trialNCT04003974CompletedPhase 2Interventional

Efficacy and Safety of Losmapimod in Subjects With Facioscapulohumeral Muscular Dystrophy (FSHD)

SponsorFulcrum TherapeuticsEnrollment80Facioscapulohumeral Muscular Dystrophy (FSHD)
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a study to evaluate the safety and efficacy of Losmapimod in treating patients with Facioscapulohumeral Muscular Dystrophy (FSHD) over 48 weeks.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

17 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • Ottawa Hospital Research Institute

    Ottawa, Ontario, Canada

  • Montreal Neurological Institute and Hospital

    Montreal, Quebec, Canada

France
  • Chu de Nice- Chu Pasteur2

    Nice, France

Spain
  • Hospital de la Sta Creu I St Pau

    Barcelona, Spain

  • Hospital Uip la Fe

    Valencia, Spain

United States
  • University of California Irvine

    Irvine, California, United States

  • University of California Los Angeles (ucla)

    Los Angeles, California, United States

  • University of Florida

    Gainesville, Florida, United States

  • University of Kansas Medical Center

    Kansas City, Kansas, United States

  • Kennedy Krieger Institute

    Baltimore, Maryland, United States

  • University of Massachusetts Memorial Medical Center

    Worcester, Massachusetts, United States

  • Washington University School of Medicine

    St Louis, Missouri, United States

  • University of Rochester Medical Center

    Rochester, New York, United States

  • Ohio State University

    Columbus, Ohio, United States

  • University of Utah

    Salt Lake City, Utah, United States

  • Virginia Commonwealth University

    Richmond, Virginia, United States

  • University of Washinton Medical Center

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

LosmapimodPlacebo
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
9 Aug 2019
Primary completion
28 Jan 2021
Completion
28 Jan 2021
Last update posted
10 Jul 2024
Registered enrollment
80
Registry id
NCT04003974

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 11 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.