Clinical trialNCT04030195CompletedPhase 1/PHASE2Interventional

Dose-escalation Study of Safety of PBCAR20A in Subjects With r/r NHL or r/r CLL/SLL

SponsorPrecision BioSciences, Inc.Enrollment18B-cell Chronic Lymphocytic LeukemiaB-cell Non Hodgkin LymphomaChronic Lymphocytic LeukemiaChronic Lymphoid Leukemia in RelapseLeukemia, Lymphocytic, ChronicLymphoma, Non-Hodgkin+3 more conditions

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a Phase 1/2a, nonrandomized, open-label, parallel assignment, single-dose, dose-escalation, and dose-expansion study to evaluate the safety and clinical activity of PBCAR20A in adult subjects with r/r B-cell NHL or r/r CLL/SLL.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Alan List, MD
Precision BioSciences, Inc.
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

City of Hope
Duarte, California, United States
Stanford University
Stanford, California, United States
Columbia University
New York, New York, United States
Cleveland Clinic
Cleveland, Ohio, United States
Md Anderson Cancer Center
Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

CyclophosphamideFludarabine

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 24 Mar 2020
Primary completion: 24 Jun 2021
Completion: 24 Jun 2021
Last update posted: 31 Jan 2023
Registered enrollment: 18
Registry id: NCT04030195

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.