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Clinical trialNCT04056065CompletedPhase 2Interventional

PMZ-2010 (Centhaquine) as a Resuscitative Agent for Hypovolemic Shock

SponsorPharmazz, Inc.Enrollment50Blood LossHypovolemic Shock
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a prospective, multi-centric, randomized, double-blind, parallel, controlled phase-II efficacy clinical study of PMZ-2010 therapy in patients with hypovolemic shock. Centhaquine is highly safe and well tolerated. Toxicological studies showed high safety margin in preclinical studies. Its safety and tolerability has been demonstrated in a human phase I study in 25 subjects (CTRI/2014/06/004647; NCT02408731).

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

India
  • Seven Star Hospital

    Nagpur, Maha, India

  • Kle'S Dr. Prabhakar Kore Hospital & Medical Research Centre

    Belagavi, India

  • Post Graduate Institute of Medical Education and Research

    Chandigarh, India

  • Institute of Postgraduate Medical Education & Research and Sskm Hospital

    Kolkata, India

  • Dayanand Medical College & Hospital

    Ludhiana, India

  • New Era Hospital & Research Institute

    Nagpur, India

  • Oriana Hospital

    Varanasi, India

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

CenthaquineNormal Saline
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
29 May 2017
Primary completion
19 Sept 2018
Completion
21 Oct 2018
Last update posted
14 Aug 2019
Registered enrollment
50
Registry id
NCT04056065

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.