Clinical trialNCT04065399RecruitingPhase 1/PHASE2Interventional

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

SponsorSyndax PharmaceuticalsEnrollment447Acute Leukemia of Ambiguous LineageAcute Lymphoblastic LeukemiaAcute Myeloid LeukemiaMixed Lineage Acute LeukemiaMixed Phenotype Acute Leukemia

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Angela R Smith, M.D.
Syndax Pharmaceuticals
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

57 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia

Peter Maccallum Cancer Centre (pmcc)
Melbourne, Victoria, Australia
Active, not recruiting
Royal Melbourne Hospital (rmh)
Parkville, Victoria, Australia
Active, not recruiting
Alfred Hospital
Melbourne, Australia
Shaun Fleming, MD
Recruiting
Sir Charles Gairdner Hospital
Nedlands, Australia
Carolyn Grove, MD
Recruiting
Royal North Shore Hospital
Saint Leonards, Australia
Matthew Greenwood, MD
Recruiting

Canada

the Hospital for Sick Children
Toronto, Canada
Active, not recruiting
University Health Network
Toronto, Canada
Andre Schuh, MD
Recruiting

France

Hospital Saint-Louis - Aphp
Paris, France
Emmanuel Raffoux
Recruiting
Centre Hospitalier Universitaire (chu) de Bordeaux
Pessac, France
Arnaud Pigneux
Recruiting
Centre Hospitalier Lyon Sud
Pierre-Bénite, France
Mael Heiblig
Recruiting
Institut Gustave Roussy-Gustave Roussy Cancer Center -Ditep
Villejuif, France
Stephanie De Botton
Recruiting

Germany

University Hospital of Ulm, Universitatsklinikum Ulm
Ulm, Baden-Wurttemberg, Germany
Hartmut Doehner
Recruiting
Universitaetsklinikum Essen (aor)
Essen, Germany
Withdrawn
Universitaetsmedizin Greifswald
Greifswald, Germany
Completed
Universitaetsmedizin Der Johannes
Gutenberg, Germany
Michael Kuehn
Recruiting
Universitaetsklinikum Hamburg-Eppendorf
Hamburg, Germany
Franziska Westendorf
Recruiting
University of Leipzig
Leipzig, Germany
Madlen Jentzsch
Recruiting
Klinikum Nuernberg Nord
Nuremberg, Germany
Completed

Israel

Rambam Health Care Campus (rhcc)
Haifa, Israel
Avraham Frisch
Recruiting
Hadassah Medical Center- Ein Kerem
Jerusalem, Israel
Boaz Nachmias
Recruiting
Shaare Zedek Medical Center
Jerusalem, Israel
Yishai Ofran
Recruiting
Galilee Medical Center
Nahariya, Israel
Galia Stemer
Recruiting
Rabin Medical Center
Petah Tikva, Israel
Ofir Wolach
Recruiting
Sheba Medical Center
Ramat Gan, Israel
Irina Armitai
Recruiting

Italy

Irccs Azienda Ospedaliero Universitaria Di Bologna
Bologna, Italy
Cristina Papayannidis
Recruiting
Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori
Meldola, Italy
Irene Zacheo
Recruiting
Irccs-Istituto Europeo Di Oncologia
Milan, Italy
Enrico Derenzini
Recruiting
Universita Cattolica Fondazione Policlinico Agostino Gemelli
Roma, Italy
Patrizia Chiusolo
Recruiting
S Bortolo Hospital Aulss 8 Berica
Vicenza, Italy
Giorgia Scotton
Recruiting

Lithuania

Vilnius University Hospital Santaros Klinikos
Vilnius, Lithuania
Andrius Zucenka
Recruiting

Netherlands

Princess Maxima Center for Pediatric Oncology
Utrecht, Netherlands
Michael Zwaan
Recruiting

Puerto Rico

Hospital Centro Comprensivo de Cancer Upr
San Juan, Puerto Rico
Alexis Cruz-Chacon
Recruiting

Spain

Institut Catala D'Oncologia (ico) - Hospital Duran I Reynals
L'Hospitalet de Llobregat, Spain
Montserrat Arnan Sangerman
Recruiting
Hospital Universitario Virgen del Rocio
Seville, Spain
Eduardo Rodriguez-Arboli
Recruiting
Hospital Universitari I Politecnic la Fe de Valencia
Valencia, Spain
Pau Montesinos Fernandez
Recruiting

United States

City of Hope Comprehensive Cancer Center
Duarte, California, United States
Active, not recruiting
University of California Care Medical Group - Norris Comprehensive Cancer Center and Hospital
Los Angeles, California, United States
Completed
Stanford Cancer Institute
Palo Alto, California, United States
Active, not recruiting
University of Colorado
Aurora, Colorado, United States
Christine McMahon
Recruiting
Florida Cancer Specialists and Research Institute
Sarasota, Florida, United States
Active, not recruiting

17 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 5 Nov 2019
Primary completion: 15 Dec 2027
Completion: 15 Dec 2027
Last update posted: 18 Mar 2026
Registered enrollment: 447
Registry id: NCT04065399

Cross-registrations

EU-CTR / CTIS (EudraCT)2020-004104-34

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.