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Clinical trialNCT04088318UnknownPhase 2Interventional

A Study to Investigate OQL011 on VEGFR Inhibitor-Associated Hand-Foot Skin Reaction in Cancer Patients

SponsorOnQuality Pharmaceuticals (USA) LLCEnrollment170Hand-Foot Skin Reaction (HFSR)
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Hand-Foot Skin Reaction (HFSR) is a common adverse event induced by Vascular Endothelial Growth Receptor Inhibitor (VEGFRi) treatment in cancer patients. The main purpose of this study is to evaluate the safety and efficacy of OQL011 compared to vehicle ointment in treating patients with moderate to severe VEGFRi-associated HFSR. This study will also identify an optimal dosage for Phase III study and explore the pharmacokinetics profile of OQL011 in HFSR patients.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

33 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

China
  • Nantong Tumor Hospital

    Nantong, Jiangsu, China

  • Taizhou People'S Hospital

    Taizhou, Jiangsu, China

  • Affiliated Hospital of Jiangnan University

    Wuxi, Jiangsu, China

  • the Affiliated Hospital of Xuzhou Medical University

    Xuzhou, Jiangsu, China

  • Huashan Hospital Affiliated To Fudan University

    Shanghai, Shanghai Municipality, China

  • Shanghai Sixth People'S Hospital

    Shanghai, Shanghai Municipality, China

  • Shanghai Tenth People'S Hospital

    Shanghai, Shanghai Municipality, China

  • Tongren Hospital Affiliated To Shanghai Jiaotong University School of Medicine

    Shanghai, Shanghai Municipality, China

  • Xinhua Hospital Affiliated To Shanghai Jiaotong University School of Medicine

    Shanghai, Shanghai Municipality, China

  • Zhejiang Provincial People'S Hospital

    Hangzhou, Zhejiang, China

India
  • S.P Medical College & Ag Hospitals, Bikaner

    Bīkaner, Dimhans, India

  • Kiran Multi Super Speciality Hospital & Research Center

    Surat, Gujarat, India

  • Kailash Cancer Hospital and Research Center

    Vadodara, Gujarat, India

  • Aadhar Health Institute

    Hisar, Haryana, India

  • Noble Hospital, Pune

    Hisar, Haryana, India

  • Oncoville Cancer Hospital and Research Center

    Bangalore, Karnataka, India

  • Mumbai Oncocare Centre

    Mumbai, Maharashtra, India

  • Hcg Manavata Cancer Centre, Nashik

    Naka, Nashik, India

United States
  • Western Regional Medical Center

    Goodyear, Arizona, United States

  • Innovative Clinical Research Institute

    Whittier, California, United States

  • University of Colorado Cancer Center

    Aurora, Colorado, United States

  • Yale University - Hospital

    New Haven, Connecticut, United States

  • Ap Medical Research

    Miami, Florida, United States

  • Northwestern University - Hospital

    Chicago, Illinois, United States

  • University of Louisville - Hospital

    Louisville, Kentucky, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, United States

  • Washington University School of Medicine

    St Louis, Missouri, United States

  • Innovative Clinical Research Institute

    Henderson, Nevada, United States

  • Memorial Sloan-Kettering Cancer Center

    New York, New York, United States

  • Montefiore Einstein Center for Cancer Care

    The Bronx, New York, United States

  • Gabrail Cancer Centre

    Canton, Ohio, United States

  • Ohio State University Dermatology

    Columbus, Ohio, United States

  • Md Anderson Cancer Center

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

OQL011Vehicle Ointment
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
9 Dec 2019
Primary completion
26 Feb 2024
Completion
30 Jun 2024
Last update posted
4 Mar 2024
Registered enrollment
170
Registry id
NCT04088318

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.