Clinical trialNCT04115514Active, not recruitingPhase 2Interventional

Treatment of ARDS With Instilled T3

SponsorUniversity of MinnesotaEnrollment68ARDS, HumanLung InflammationLung, WetPulmonary EdemaThyroid

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

It is hypothesized that instillation of Liothyronine Sodium (T3) into the airspace will be safe, well tolerated, and will increase alveolar fluid clearance and decrease inflammation in patients with ARDS, reflected in improved oxygenation index (OI) and oxygenation saturation index (OSI).

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

David H Ingbar, MD
University of Minnesota
Study ChairKOL profile →
clinicaltrials.gov ↗
Ronald A Reikoff, MD
University of Minnesota
Principal Investigator
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Timothy P Rich, MD
University of Minnesota
Study Director
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

2 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

M Health Fairview Southdale Hospital
Edina, Minnesota, United States
East Bank Hospital - M Health Fairview University of Minnesota Medical Center
Minneapolis, Minnesota, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Liothyronine Sodium modified formulation specifically for airway instillation

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Mar 2020
Primary completion: 31 Oct 2026
Completion: 31 Oct 2026
Last update posted: 7 Apr 2026
Registered enrollment: 68
Registry id: NCT04115514

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.