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Clinical trialNCT04128319TerminatedPhase 3Interventional

T-Guard as Treatment for Steroid Refractory Acute GVHD (BMT CTN 1802)

SponsorXenikosEnrollment3Steroid-Refractory Acute Graft Versus Host Disease
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The study is designed as an open-label, single arm Phase III, multicenter trial to evaluate the efficacy and safety of T-Guard treatment in patients with Steroid-Refractory acute Graft versus Host Disease (SR-aGVHD).
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

24 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • City of Hope National Medical Center

    Duarte, California, United States

  • Children'S Hospital Los Angeles

    Los Angeles, California, United States

  • Children'S National Medical Center

    Washington D.C., District of Columbia, United States

  • H. Lee Moffitt Cancer Center

    Tampa, Florida, United States

  • Emory University

    Atlanta, Georgia, United States

  • Indiana University

    Indianapolis, Indiana, United States

  • University of Kansas

    Westwood, Kansas, United States

  • Johns Hopkins University

    Baltimore, Maryland, United States

  • University of Maryland

    Baltimore, Maryland, United States

  • University of Michigan

    Ann Arbor, Michigan, United States

  • University of Minnesota

    Minneapolis, Minnesota, United States

  • Mayo Clinic

    Rochester, Minnesota, United States

  • Washington University in St. Louis

    St Louis, Missouri, United States

  • University of Nebraska

    Omaha, Nebraska, United States

  • Mount Sinai Medical Center

    New York, New York, United States

  • Cincinnati Children'S Hospital Medical Center

    Cincinnati, Ohio, United States

  • Ohio State University

    Columbus, Ohio, United States

  • Oregon Health & Science University

    Portland, Oregon, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, United States

  • Baylor College of Medicine

    Houston, Texas, United States

  • University of Utah

    Salt Lake City, Utah, United States

  • Fred Hutchinson Cancer Research Center

    Seattle, Washington, United States

  • University of Wisconsin

    Madison, Wisconsin, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

T-Guard
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
21 Nov 2019
Primary completion
17 Feb 2020
Completion
17 Feb 2020
Last update posted
16 Dec 2021
Registered enrollment
3
Registry id
NCT04128319
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.