Clinical trialNCT04131829RecruitingPhase 1/PHASE2Interventional

Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD

SponsorYale UniversityEnrollment100Obsessive-Compulsive Disorder

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The proposed randomized, double-blind research study will use functional magnetic resonance neuroimaging using state-of-the-art HCP acquisition protocols and analytic pipelines, to identify predictors and correlates of response to an accepted first-line pharmacological treatment for obsessive-compulsive disorder.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Christopher Pittenger, MD, PhD
Professor of Psychiatry; Director, Yale OCD Research Clinic
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Yale Ocd Research Clinic - Cmhc/cnru, 34 Park St
New Haven, Connecticut, United States
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Fluoxetine - delayed treatmentFluoxetine - immediate treatment

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 14 Oct 2019
Primary completion: 30 Jun 2026
Completion: 31 Dec 2026
Last update posted: 14 Aug 2025
Registered enrollment: 100
Registry id: NCT04131829

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.