Clinical trialNCT04165109RecruitingObservational

Trial-Ready Cohort-Down Syndrome (TRC-DS)

SponsorUniversity of Southern CaliforniaEnrollment550Alzheimer DiseaseDementiaDown Syndrome

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Michael Rafii, MD, PhD
USC Alzheimer's Therapeutic Research Institute (ATRI)
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

22 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

France

Institut Jerome Lejeune
Paris, France, France
Anne-Sophie Rebillat, MD PhD
Recruiting

Ireland

Institute of Memory & Cognition, Tallaght University Hospital
Dublin, Ireland, Ireland
Sean Kennelly, MD PhD
Recruiting

Spain

Sant Pau Biomedical Research Institute (iib Sant Pau)
Barcelona, Spain
Juan Fortea, MD, PhD
Recruiting

United Kingdom

University of Cambridge, Co-Enrolling Through Abc-Ds Only
Cambridge, United Kingdom
Shahid Zaman, MD, PhD
Recruiting

United States

Barrow Neurological Institute
Phoenix, Arizona, United States
Anna Burke, MD
Recruiting
University of California, Irvine School of Medicine, Co-Enrolling Through Abc-Ds Only
Orange, California, United States
Ira Lott
Recruiting
Linda Crnic Institute for Down Syndrome, University of Colorado
Aurora, Colorado, United States
Joaquin Espinosa, PhD
Recruiting
Advocate Medical Group Adult Down Syndrome Center
Park Ridge, Illinois, United States
Brian Chicoine, MD
Not, yet, recruiting
Indiana University
Indianapolis, Indiana, United States
Jill Fodstad, PhD
Recruiting
University of Kansas Medical Center
Kansas City, Kansas, United States
Lauren T Ptomey, PhD, RD, LD
Recruiting
University of Kentucky, Co-Enrolling Through Abc-Ds Only
Lexington, Kentucky, United States
Frederick Schmitt, PhD
Recruiting
Massachusetts General Hospital, Co-Enrolling Through Abc-Ds Only
Boston, Massachusetts, United States
Herminia Herminia Diana Rosas
Recruiting
Washington University, St. Louis
St Louis, Missouri, United States
Beau Ances, MD, PhD
Recruiting
Cleveland Clinic, Lou Ruvo Center for Brain Health, Las Vegas
Las Vegas, Nevada, United States
Charles Bernick, MD
Not, yet, recruiting
New York State Institute for Basic Research in Developmental Disabilities (sibrdd), Co-Enrolling Through Abc-Ds Only
Staten Island, New York, United States
Sharon Krinsky-McHale, PhD
Recruiting
Case Western Reserve University
Beachwood, Ohio, United States
Rajeet Shrestha, MD
Recruiting
University of Cincinnati
Cincinnati, Ohio, United States
Russell Sawyer, MD
Not, yet, recruiting
Oregon Health & Science University
Portland, Oregon, United States
Aimee Pierce, MD
Not, yet, recruiting
University of Pittsburgh, Co-Enrolling Through Abc-Ds Only
Pittsburgh, Pennsylvania, United States
Benjamin Handen
Recruiting
Vanderbilt University Medical Center Center for Cognitive Medicine
Nashville, Tennessee, United States
Paul Newhouse, MD
Recruiting
University of Texas Health San Antonio, Glenn Biggs Institute for Alzheimer'S & Neurodegenerative Diseases
San Antonio, Texas, United States
Sarah Savoia, PAC-C
Recruiting
University of Wisconsin - Madison, Waisman Center, Co-Enrolling Through Abc-Ds Only
Madison, Wisconsin, United States
Bradley Christian
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 7 Jun 2021
Primary completion: 31 Dec 2027
Completion: 31 Dec 2027
Last update posted: 18 May 2026
Registered enrollment: 550
Registry id: NCT04165109

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.