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Clinical trialNCT04180371Active, not recruitingPhase 1/PHASE2Interventional

Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression

SponsorBicycleTx LimitedEnrollment288Advanced Solid Tumor Historically Known for High EphA2 ExpressionGastric/Upper Gastrointestinal CancerHead and Neck CancerNon-small Cell Lung CancerOvarian CancerTriple Negative Breast Cancer+1 more conditions
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

28 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Belgium
  • Cliniques Universitaires Saint-Luc

    Brussels, Belgium

  • Institut Jules Bordet

    Brussels, Belgium

  • Antwerp University Hospital (uza)

    Edegem, Belgium

  • Universitair Ziekenhuis Gent (uz)

    Ghent, Belgium

South Korea
  • Gachon University Gil Medical Center

    Incheon, South Korea

  • Severance Hospital, Yonsei University Health System

    Seoul, South Korea

Spain
  • Hospital Universitario Vall D'Hebron

    Barcelona, Spain

  • Institut Catala D'Oncologia - L'Hospitalet

    Barcelona, Spain

  • Centro Integral Oncologico Clara Campal

    Madrid, Spain

  • Hospital Fundación Jimenez Diaz

    Madrid, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, Spain

United Kingdom
  • Sarah Cannon Research Institute Uk

    London, United Kingdom, United Kingdom

  • the Christie Nhs Foundation Trust

    Manchester, United Kingdom, United Kingdom

  • Cambridge University Hospitals Nhs Foundation Trust

    Cambridge, United Kingdom

  • the Leeds Teaching Hospitals Nhs Trust of Trust Headquarters, St James'S University Hospital

    Leeds, United Kingdom

  • Sir Bobby Robson Cancer Trials Research Centre, the Northern Center for Cancer Care, Freeman Hospital

    Newcastle upon Tyne, United Kingdom

United States
  • California Cancer Associates for Research and Excellence, Inc.

    Encinitas, California, United States

  • University of California - Irvine Medical Center

    Orange, California, United States

  • Sarah Cannon Research Institute at Healthone

    Denver, Colorado, United States

  • Florida Cancer Specialists

    Sarasota, Florida, United States

  • Barbara Ann Karmanos Cancer Institute

    Detroit, Michigan, United States

  • Comprehensive Cancer Centers of Nevada

    Las Vegas, Nevada, United States

  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center

    New York, New York, United States

  • Stephenson Cancer Center (oklahoma University)

    Oklahoma City, Oklahoma, United States

  • Sidney Kimmel Cancer Center at Thomas Jefferson University

    Philadelphia, Pennsylvania, United States

  • Sarah Cannon and Hca Research Institute

    Nashville, Tennessee, United States

  • Md Anderson Cancer Center

    Houston, Texas, United States

  • Virginia Cancer Specialists

    Fairfax, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
7 Nov 2019
Primary completion
31 Jul 2026
Completion
31 Jul 2027
Last update posted
17 Nov 2025
Registered enrollment
288
Registry id
NCT04180371

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.