Clinical trialNCT04193878TerminatedPhase 3Interventional

ARrest RESpiraTory Failure From PNEUMONIA

SponsorStanford UniversityEnrollment465Acute Respiratory FailureCOVID-19 PneumoniaHypoxemiaPneumonia

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This research study seeks to establish the effectiveness of a combination of an inhaled corticosteroid and a beta agonist compared to placebo for the prevention of acute respiratory failure (ARF) in hospitalized patients with pneumonia and hypoxemia.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Emir Festic, MD
Mayo Clinic
Principal Investigator
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Joseph Levitt, MD
Stanford University
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

12 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama Birmingham - Main & Highlands
Birmingham, Alabama, United States
Mayo Clinic - Scottsdale
Scottsdale, Arizona, United States
University of Arizona - Main & South Campus
Tucson, Arizona, United States
Stanford University
Palo Alto, California, United States
University of Florida
Gainesville, Florida, United States
Mayo Clinic - Jacksonville
Jacksonville, Florida, United States
Tulane University - Main & Bumc
New Orleans, Louisiana, United States
Johns Hopkins University - Main Campus & Bayview
Baltimore, Maryland, United States
University of Maryland
Baltimore, Maryland, United States
Mayo Clinic - Rochester
Rochester, Minnesota, United States
New York University - Langone Health
New York, New York, United States
Temple University
Philadelphia, Pennsylvania, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Inhaled budesonide and formoterolInhaled placebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Jun 2020
Primary completion: 22 Jul 2025
Completion: 22 Jul 2025
Last update posted: 6 Aug 2026
Registered enrollment: 465
Registry id: NCT04193878

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.