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Clinical trialNCT04224857CompletedPhase 1Interventional

SAD/MAD Study in Healthy Subjects and Adults With UC to Evaluate Safety, Tolerability, PK, PD of AMT-101

SponsorApplied Molecular TransportEnrollment52Ulcerative Colitis
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

A randomized, double-blind placebo-controlled first in human study in approximately 36 male healthy subjects and approximately 20 male and female patients with active UC who have had an inadequate response to or demonstrated intolerance to 5-ASA.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

4 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Georgia
  • Llc Arensia Exploratory Medicine

    Tbilisi, Georgia

Germany
  • Charité Research Organisation Gmbh

    Berlin, Germany

Moldova
  • Ics Arensia Exploratory Medicine Srl

    Chisinau, Moldova

Ukraine
  • Medical Center of Harmoniya Krasy, Department of Clinical Trials

    Kyiv, Ukraine

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

AMT-101Placebo
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
1 Apr 2019
Primary completion
30 Apr 2020
Completion
30 Apr 2020
Last update posted
28 Oct 2020
Registered enrollment
52
Registry id
NCT04224857
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.