Clinical trialNCT04269902RecruitingPhase 3Interventional

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

SponsorNational Cancer Institute (NCI)Enrollment247Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Deborah M Stephens
SWOG Cancer Research Network
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

631 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Bcca-Vancouver Cancer Centre
Vancouver, British Columbia, Canada
Alina S. Gerrie
Recruiting
Cancercare Manitoba
Winnipeg, Manitoba, Canada
Versha Banerji
Recruiting
Atlantic Health Sciences Corporation-Saint John Regional Hospital
Saint John, New Brunswick, Canada
Alfonso Rivera Duarte
Recruiting
Qeii Health Sciences Centre/nova Scotia Health Authority
Halifax, Nova Scotia, Canada
Active, not recruiting
Lakeridge Health Oshawa
Oshawa, Ontario, Canada
Active, not recruiting
Ottawa Hospital and Cancer Center-General Campus
Ottawa, Ontario, Canada
David A. Macdonald
Recruiting
Jewish General Hospital
Montreal, Quebec, Canada
Tanya Skamene
Recruiting
Allan Blair Cancer Centre
Regina, Saskatchewan, Canada
Active, not recruiting

United States

University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, United States
Active, not recruiting
Alaska Breast Care and Surgery Llc
Anchorage, Alaska, United States
Suspended
Alaska Oncology and Hematology Llc
Anchorage, Alaska, United States
Suspended
Alaska Women'S Cancer Care
Anchorage, Alaska, United States
Suspended
Anchorage Associates in Radiation Medicine
Anchorage, Alaska, United States
Suspended
Anchorage Oncology Centre
Anchorage, Alaska, United States
Suspended
Anchorage Radiation Therapy Center
Anchorage, Alaska, United States
Suspended
Katmai Oncology Group
Anchorage, Alaska, United States
Suspended
Providence Alaska Medical Center
Anchorage, Alaska, United States
Suspended
Fairbanks Memorial Hospital
Fairbanks, Alaska, United States
Suspended
Cancer Center at Saint Joseph'S
Phoenix, Arizona, United States
Active, not recruiting
Banner University Medical Center - Tucson
Tucson, Arizona, United States
Krishna Rekha Moturi
Recruiting
University of Arizona Cancer Center-North Campus
Tucson, Arizona, United States
Krishna Rekha Moturi
Recruiting
Mercy Hospital Fort Smith
Fort Smith, Arkansas, United States
Suspended
Chi Saint Vincent Cancer Center Hot Springs
Hot Springs, Arkansas, United States
Suspended
Nea Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
Jonesboro, Arkansas, United States
Muhammad Raza
Recruiting
Kaiser Permanente-Anaheim
Anaheim, California, United States
Ashraf R. Aziz
Recruiting
Mission Hope Medical Oncology - Arroyo Grande
Arroyo Grande, California, United States
Active, not recruiting
Kaiser Permanente-Baldwin Park
Baldwin Park, California, United States
Ashraf R. Aziz
Recruiting
Kaiser Permanente-Bellflower
Bellflower, California, United States
Ashraf R. Aziz
Recruiting
Providence Saint Joseph Medical Center/disney Family Cancer Center
Burbank, California, United States
Suspended
Marshall Cancer Center
Cameron Park, California, United States
Joseph M. Tuscano
Recruiting
Mercy Cancer Center - Carmichael
Carmichael, California, United States
Active, not recruiting
Mercy San Juan Medical Center
Carmichael, California, United States
Active, not recruiting
Enloe Medical Center
Chico, California, United States
Joseph M. Tuscano
Recruiting
Uc Irvine Health Cancer Center-Newport
Costa Mesa, California, United States
Catherine C. Coombs
Recruiting
City of Hope Comprehensive Cancer Center
Duarte, California, United States
Alexey V. Danilov
Recruiting
Mercy Cancer Center - Elk Grove
Elk Grove, California, United States
Active, not recruiting
Kaiser Permanente-Fontana
Fontana, California, United States
Ashraf R. Aziz
Recruiting
Kaiser Permanente South Bay
Harbor City, California, United States
Ashraf R. Aziz
Recruiting
City of Hope Seacliff
Huntington Beach, California, United States
Alexey V. Danilov
Recruiting
City of Hope at Irvine Lennar
Irvine, California, United States
Alexey V. Danilov
Recruiting

591 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 2 Mar 2021
Primary completion: 1 Oct 2028
Completion: 1 Oct 2028
Last update posted: 9 Jul 2026
Registered enrollment: 247
Registry id: NCT04269902

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.