Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors
Summary
The lay summary the sponsor registered on ClinicalTrials.gov.
Investigators
The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.
- Erin Trovillion, M.D.
Atrium Health Levine Children's Hospital - Carolinas Medical Center
Principal Investigator - Kyle Jackson, M.D.
Indiana University School of Medicine, Riley Hospital for Children
Principal Investigator - Lars Wagner, M.D.
Children's Hospital Medical Center, Cincinnati
Principal Investigator - Meghann McManus, D.O.
Sarah Cannon Research Institute, Pediatric Hematology & Oncology
Principal Investigator - Mia Weiss, M.D.
Washington University School of Medicine
Principal Investigator - Michael Deel, M.D.
Children's Hospital Medical Center, Cincinnati
Principal Investigator - Patrick Thompson, M.D.
UNC Chapel Hill - North Carolina Cancer Hospital
Principal Investigator - William Thomas Cash, M.D.
Children's Healthcare of Atlanta - Arthur M. Blank Hospital
Principal Investigator
A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.
Sites
11 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.
- Phoenix Children'S Hospital
Phoenix, Arizona, United States
- Ucsf, Mission Bay - Benioff Children'S Hospital
San Francisco, California, United States
- Children'S National Research Institute - Children'S National Hospital
Washington D.C., District of Columbia, United States
- Children'S Healthcare of Atlanta - Arthur M. Blank Hospital
Atlanta, Georgia, United States
- Indiana University School of Medicine, Riley Hospital for Children
Indianapolis, Indiana, United States
- Washington University - St. Louis
St Louis, Missouri, United States
- University of North Carolina at Chapel Hill - North Carolina Cancer Hospital
Chapel Hill, North Carolina, United States
- Atrium Health Levine Children'S Hospital - Carolinas Medical Center
Charlotte, North Carolina, United States
- Duke University Children'S Hospital and Health Center
Durham, North Carolina, United States
- Cincinnati Children'S Hospital Medical Center
Cincinnati, Ohio, United States
- Sarah Cannon Research Institute, Pediatric Hematology & Oncology
Nashville, Tennessee, United States
Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.
Drugs studied
The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.
Registration & key dates
Registry attributes as recorded on the ClinicalTrials.gov study record.
- Start
- 25 Oct 2021
- Primary completion
- 31 Dec 2026
- Completion
- 31 Dec 2026
- Last update posted
- 30 Jul 2026
- Registered enrollment
- 20
- Registry id
- NCT04337177
Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.