Clinical trialNCT04341779Active, not recruitingInterventional

Simplifying Treatment and Monitoring for HIV (STREAM HIV)

SponsorUniversity of WashingtonEnrollment539HIV-1-infectionHIV/AIDS

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study seeks to determine the clinical efficacy and cost effectiveness of implementing an integrated model for HIV monitoring using point of care (POC) tenofovir (TFV) adherence testing and POC viral load (VL) monitoring in improving ART adherence, maintaining durable VL suppression, and improving retention in care among HIV-positive individuals initiating first-line tenofovir disoproxil fumarate (TDF)-based ART in South Africa.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Nigel Garett, MBBS, PHD
Centre for the AIDS Programme of Research in South Africa (CAPRISA)
Principal Investigator
clinicaltrials.gov ↗
Paul Drain, MD, MPH
University of Washington
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

South Africa

Centre for the Aids Programme of Research in South Africa (caprisa), University of Kwazulu-Natal
Durban, KwaZulu-Natal, South Africa

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 4 Feb 2021
Primary completion: 30 Jun 2025
Completion: 31 Dec 2026
Last update posted: 19 Feb 2026
Registered enrollment: 539
Registry id: NCT04341779

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.