Clinical trialNCT04347382CompletedPhase 3Interventional

Honey & Nigella Sativa Trial Against COVID-19

SponsorSohaib AshrafEnrollment313Coronavirus InfectionSars-CoV2

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To evaluate the effectiveness of Nigella Sativa and honey stirred in 250 ml of distilled water 12 hourly till patient becomes asymptomatic or a maximum of 14 days with standard hospital care versus standard hospital care alone with placebo capsule and 250 ml water, in clearing the COVID-19 nucleic acid from throat and nasal swab, lowering disease detrimental effects on HRCT chest/X-ray and severity of symptoms along with duration of hospital stay till day 14th day of follow up and 30 days mortality (primary outcomes).

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Ayesha Hamayun, MBBS, PhD
Shaikh Khalifa Bin Zayed Al-Nahyan Medical & Dental College, Lahore
Principal Investigator
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Muhammad Ahmad Imran, MBBS
Shaikh Zayed Hospital, Lahore
Principal Investigator
clinicaltrials.gov ↗
Muhammad Ashraf, DVM, PhD
University Of Veterinary & Animal Sciences, Lahore
Study Chair
clinicaltrials.gov ↗
Shoaib Ashraf, PhD
Massachusetts General Hospital, Harvard Medical School, USA
Study Director
clinicaltrials.gov ↗
Sohaib Ashraf, MBBS
Federal Post-Graduate Medical Institute, Lahore
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

2 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Pakistan

Federal Post-Graduate Medical Institute, Shaikh Zayed Hospital
Lahore, Punjab Province, Pakistan
Services Institute of Medical Sciences, Services Hospital
Lahore, Punjab Province, Pakistan

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Honey preparationNigella Sativa / Black CuminPlacebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Apr 2020
Primary completion: 30 Aug 2020
Completion: 30 Aug 2020
Last update posted: 12 Nov 2020
Registered enrollment: 313
Registry id: NCT04347382

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 11 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.