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Clinical trialNCT04404595Active, not recruitingPhase 1/PHASE2Interventional

Claudin18.2 CAR-T (CT041) in Patients With Gastric, Pancreatic Cancer, or Other Specified Digestive Cancers

SponsorCARsgen Therapeutics Co., Ltd.Enrollment110Gastric CancerPancreatic Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

A Phase 1b/2, open label, multi-center, clinical study of Chimeric Antigen Receptor T Cells (CAR-T) targeting claudin18.2 in patients with advanced gastric, pancreatic or other specified digestive system cancers

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

16 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • Princess Margaret Hospital

    Toronto, Ontario, Canada

United States
  • City of Hope

    Duarte, California, United States

  • University of Southern California

    Los Angeles, California, United States

  • Ucsd

    San Diego, California, United States

  • Ucsf

    San Francisco, California, United States

  • Moffitt Cancer Center

    Tampa, Florida, United States

  • University of Kansas Cancer Center

    Kansas City, Kansas, United States

  • Karmanos Cancer Center

    Detroit, Michigan, United States

  • Mayo Cancer Hospital

    Rochester, Minnesota, United States

  • Northwell Cancer Institute

    New Hyde Park, New York, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, United States

  • the Mount Sinai Hospital

    New York, New York, United States

  • Ohio State University

    Columbus, Ohio, United States

  • Tx Oncology-Baylor Charles Sammons Cancer Center

    Dallas, Texas, United States

  • Md Anderson Cancer Center

    Houston, Texas, United States

  • Froedtert Hospital and the Medical College of Wisconsin

    Milwaukee, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

CT041
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
23 Oct 2020
Primary completion
1 Jun 2025
Completion
1 Sept 2035
Last update posted
8 Jan 2025
Registered enrollment
110
Registry id
NCT04404595

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.