Clinical trialNCT04412616RecruitingPhase 1Interventional

ZZ06 in Adult Patients With Advanced Solid Tumor Malignancies

SponsorChangchun Intellicrown Pharmaceutical Co. LTDEnrollment60Advanced EGFR Positive Solid Tumor

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a Phase 1, Multicenter, Open-label study to assess the safety, tolerability and preliminary efficacy of ZZ06 in participants with all Adult Patients with Advanced EGFR-positive Solid Tumor Malignancies who are not able to have current standard anti-tumor therapies. The purpose of this study is to determine the maximum tolerated dose (MTD) , to characterise the safety, pharmacokinetics (PK), immunogenicity, pharmacodynamics (PD) and anti-tumor activity of ZZ06 as a single agent in adult participants with advanced solid tumors.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Sanjay Goel, MD
Montefiore Medical Center
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

China

Jilin Cancer Hospital
Changchun, Jilin, China
Not, yet, recruiting
the First Bethune Hospital of Jilin University
Changchun, Jilin, China
Songling Zhang, Ph.D
Recruiting

United States

Cedars Sinai Medical Center
Los Angeles, California, United States
Recruiting
Kansas University Cancer Center
Fairway, Kansas, United States
Recruiting
Montefiore Medical Center
The Bronx, New York, United States
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

ZZ06

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Sept 2020
Primary completion: 1 Dec 2025
Completion: 6 Jul 2026
Last update posted: 10 Jun 2025
Registered enrollment: 60
Registry id: NCT04412616

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.