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Clinical trialNCT04444921Active, not recruitingPhase 3Interventional

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients

SponsorNational Cancer Institute (NCI)Enrollment205Anal Basaloid CarcinomaAnal Canal Cloacogenic CarcinomaMetastatic Anal Squamous Cell CarcinomaRecurrent Anal Squamous Cell CarcinomaStage III Anal Cancer AJCC v8Stage IV Anal Cancer AJCC v8+1 more conditions
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

580 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Alaska Breast Care and Surgery Llc

    Anchorage, Alaska, United States

  • Alaska Oncology and Hematology Llc

    Anchorage, Alaska, United States

  • Alaska Women'S Cancer Care

    Anchorage, Alaska, United States

  • Anchorage Associates in Radiation Medicine

    Anchorage, Alaska, United States

  • Anchorage Oncology Centre

    Anchorage, Alaska, United States

  • Anchorage Radiation Therapy Center

    Anchorage, Alaska, United States

  • Katmai Oncology Group

    Anchorage, Alaska, United States

  • Providence Alaska Medical Center

    Anchorage, Alaska, United States

  • Kingman Regional Medical Center

    Kingman, Arizona, United States

  • Cancer Center at Saint Joseph'S

    Phoenix, Arizona, United States

  • Mercy Hospital Fort Smith

    Fort Smith, Arkansas, United States

  • Chi Saint Vincent Cancer Center Hot Springs

    Hot Springs, Arkansas, United States

  • Kaiser Permanente-Anaheim

    Anaheim, California, United States

  • Kaiser Permanente-Deer Valley Medical Center

    Antioch, California, United States

  • Mission Hope Medical Oncology - Arroyo Grande

    Arroyo Grande, California, United States

  • Pcr Oncology

    Arroyo Grande, California, United States

  • Kaiser Permanente-Baldwin Park

    Baldwin Park, California, United States

  • Kaiser Permanente-Bellflower

    Bellflower, California, United States

  • Providence Saint Joseph Medical Center/disney Family Cancer Center

    Burbank, California, United States

  • Kaiser Permanente Dublin

    Dublin, California, United States

  • Kaiser Permanente-Fontana

    Fontana, California, United States

  • Kaiser Permanente-Fremont

    Fremont, California, United States

  • Fresno Cancer Center

    Fresno, California, United States

  • Kaiser Permanente-Fresno

    Fresno, California, United States

  • Kaiser Permanente South Bay

    Harbor City, California, United States

  • Kaiser Permanente-Irvine

    Irvine, California, United States

  • Cedars-Sinai Medical Center

    Los Angeles, California, United States

  • Kaiser Permanente Los Angeles Medical Center

    Los Angeles, California, United States

  • Kaiser Permanente West Los Angeles

    Los Angeles, California, United States

  • Keck Medicine of Usc Koreatown

    Los Angeles, California, United States

  • Los Angeles General Medical Center

    Los Angeles, California, United States

  • Usc / Norris Comprehensive Cancer Center

    Los Angeles, California, United States

  • Kaiser Permanente-Modesto

    Modesto, California, United States

  • Usc Norris Oncology/hematology-Newport Beach

    Newport Beach, California, United States

  • Kaiser Permanente Oakland-Broadway

    Oakland, California, United States

  • Kaiser Permanente-Oakland

    Oakland, California, United States

  • Kaiser Permanente-Ontario

    Ontario, California, United States

  • Uc Irvine Health/chao Family Comprehensive Cancer Center

    Orange, California, United States

  • Kaiser Permanente - Panorama City

    Panorama City, California, United States

  • Kaiser Permanente-Rancho Cordova Cancer Center

    Rancho Cordova, California, United States

540 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
17 Nov 2020
Primary completion
31 Mar 2027
Completion
31 Mar 2027
Last update posted
2 Jul 2026
Registered enrollment
205
Registry id
NCT04444921

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.