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Clinical trialNCT04482933WithdrawnPhase 2Interventional

HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma

SponsorPediatric Brain Tumor ConsortiumEnrollment0Anaplastic Astrocytoma of BrainAnaplastic GliomaGiant Cell GlioblastomaGlioblastoma MultiformeHigh Grade GliomaHigh-grade Glioma+2 more conditions
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study is a clinical trial to assess the efficacy and confirm the safety of intratumoral inoculation of G207 (an experimental virus therapy) combined with a single 5 Gy dose of radiation in recurrent/progressive pediatric high-grade gliomas

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Holly Lindsay Md

    Aurora, Colorado, United States

  • Memorial Sloan Kettering

    New York, New York, United States

  • Upmc Children'S Hospital of Pittsburgh

    Pittsburgh, Pennsylvania, United States

  • Md Anderson Cancer Center

    Houston, Texas, United States

  • Texas Children'S Hospital

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Biological G207
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
1 Sept 2025
Primary completion
18 Dec 2025
Completion
18 Dec 2025
Last update posted
10 Feb 2026
Registered enrollment
0
Registry id
NCT04482933

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.