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Clinical trialNCT04487145CompletedPhase 4Interventional

Dihydroartemisinin-Piperaquine in the Context of Antiretroviral Therapy

SponsorUniversity of California, San FranciscoEnrollment194Drug-Drug InteractionHIV Infection
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Open-label prospective intensive pharmacokinetic study of dihydroartemisinin-piperaquine (DP) in HIV-infected children on efavirenz (EFV)-, lopinavir/ritonavir (LPV/r)-, or dolutegravir (DTG)-based antiretroviral therapy (ART) and HIV-uninfected children not on ART. All children will be malaria-uninfected at the time of enrollment.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

2 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Uganda
  • Masafu General Hospital (mgh) at Busia District, Eastern Uganda

    Masafu, Busia, Uganda

  • Baylor-Uganda Center of Excellence on Mulago Hospital Complex and Masafu General Hospital

    Kampala, Uganda

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Dihydroartemisinin-piperaquine
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
23 Nov 2020
Primary completion
11 Apr 2022
Completion
11 Apr 2022
Last update posted
14 Mar 2025
Registered enrollment
194
Registry id
NCT04487145
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.