Clinical trialNCT04511013RecruitingPhase 2Interventional

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

SponsorSWOG Cancer Research NetworkEnrollment112Acral Lentiginous MelanomaClinical Stage IV Cutaneous Melanoma AJCC v8Metastatic Cutaneous MelanomaMetastatic Malignant Neoplasm in the BrainMetastatic MelanomaMetastatic Mucosal Melanoma+1 more conditions

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Zeynep Eroglu
SWOG Cancer Research Network
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

331 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, United States
Maya Khalil
Recruiting
Thomas Hospital
Fairhope, Alabama, United States
Furhan Yunus
Recruiting
Mobile Infirmary Medical Center
Mobile, Alabama, United States
Furhan Yunus
Recruiting
Alaska Breast Care and Surgery Llc
Anchorage, Alaska, United States
Charles W. Drescher
Recruiting
Alaska Oncology and Hematology Llc
Anchorage, Alaska, United States
Charles W. Drescher
Recruiting
Alaska Women'S Cancer Care
Anchorage, Alaska, United States
Charles W. Drescher
Recruiting
Anchorage Associates in Radiation Medicine
Anchorage, Alaska, United States
Charles W. Drescher
Recruiting
Anchorage Oncology Centre
Anchorage, Alaska, United States
Charles W. Drescher
Recruiting
Anchorage Radiation Therapy Center
Anchorage, Alaska, United States
Charles W. Drescher
Recruiting
Katmai Oncology Group
Anchorage, Alaska, United States
Charles W. Drescher
Recruiting
Providence Alaska Medical Center
Anchorage, Alaska, United States
Charles W. Drescher
Recruiting
Fairbanks Memorial Hospital
Fairbanks, Alaska, United States
Nicholas DiBella
Recruiting
Mercy Hospital Fort Smith
Fort Smith, Arkansas, United States
Jay W. Carlson
Recruiting
Providence Saint Joseph Medical Center/disney Family Cancer Center
Burbank, California, United States
Charles W. Drescher
Recruiting
Epic Care-Dublin
Dublin, California, United States
Lisa Bailey
Recruiting
Bay Area Breast Surgeons Inc
Emeryville, California, United States
Lisa Bailey
Recruiting
Epic Care Partners in Cancer Care
Emeryville, California, United States
Lisa Bailey
Recruiting
Ucla / Jonsson Comprehensive Cancer Center
Los Angeles, California, United States
Bartosz Chmielowski
Recruiting
Contra Costa Regional Medical Center
Martinez, California, United States
Lisa Bailey
Recruiting
Providence Queen of the Valley
Napa, California, United States
Charles W. Drescher
Recruiting
Alta Bates Summit Medical Center - Summit Campus
Oakland, California, United States
Suspended
Bay Area Tumor Institute
Oakland, California, United States
Lisa Bailey
Recruiting
Sharp Memorial Hospital
San Diego, California, United States
Charles H. Redfern
Recruiting
Providence Medical Foundation - Santa Rosa
Santa Rosa, California, United States
Charles W. Drescher
Recruiting
Providence Santa Rosa Memorial Hospital
Santa Rosa, California, United States
Charles W. Drescher
Recruiting
Epic Care Cyberknife Center
Walnut Creek, California, United States
Lisa Bailey
Recruiting
Rocky Mountain Cancer Centers-Aurora
Aurora, Colorado, United States
Nicholas DiBella
Recruiting
the Medical Center of Aurora
Aurora, Colorado, United States
Suspended
University of Colorado Hospital
Aurora, Colorado, United States
Theresa M. Medina
Recruiting
Boulder Community Foothills Hospital
Boulder, Colorado, United States
Nicholas DiBella
Recruiting
Rocky Mountain Cancer Centers-Boulder
Boulder, Colorado, United States
Nicholas DiBella
Recruiting
Rocky Mountain Cancer Centers - Centennial
Centennial, Colorado, United States
Nicholas DiBella
Recruiting
Colorado Blood Cancer Institute
Denver, Colorado, United States
Nicholas DiBella
Recruiting
Presbyterian - Saint Lukes Medical Center - Health One
Denver, Colorado, United States
Nicholas DiBella
Recruiting
Rocky Mountain Cancer Centers-Midtown
Denver, Colorado, United States
Nicholas DiBella
Recruiting
Rocky Mountain Cancer Centers-Rose
Denver, Colorado, United States
Nicholas DiBella
Recruiting
Rose Medical Center
Denver, Colorado, United States
Suspended
the Women'S Imaging Center
Denver, Colorado, United States
Nicholas DiBella
Recruiting
Western Surgical Care
Denver, Colorado, United States
Suspended
Mountain Blue Cancer Care Center - Swedish
Englewood, Colorado, United States
Nicholas DiBella
Recruiting

291 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 6 Jan 2021
Primary completion: 30 Jun 2027
Completion: 30 Jun 2027
Last update posted: 11 Sept 2025
Registered enrollment: 112
Registry id: NCT04511013

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.