Clinical trialNCT04523961CompletedPhase 2/PHASE3Interventional

Comparative Study of Two Topical Anesthetics Prior to Fractional Nonablative Laser Treatment of the Face

SponsorMayo ClinicEnrollment22Anesthesia, LocalPhotodamaged SkinTopical and Infiltration Anesthetic Toxicity

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine the efficacy of lidocaine 2.5%/prilocaine 2.5% cream versus lidocaine 23%/tetracaine 7% ointment for topical anesthesia prior to a nonablative laser procedure.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Elika Hoss
Mayo Clinic
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Mayo Clinic in Arizona
Scottsdale, Arizona, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

2.5 g of lidocaine 23% / tetracaine 7% ointment without occlusion7.5 g lidocaine 2.5%/ prilocaine 2.5% cream with occlusion

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 8 Jan 2021
Primary completion: 19 Feb 2025
Completion: 19 Feb 2025
Last update posted: 20 Feb 2026
Registered enrollment: 22
Registry id: NCT04523961

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.