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Clinical trialNCT04527900TerminatedPhase 2Interventional

The UPPROACH (Upfront Intensity Modulated Proton Beam Therapy) Approach

SponsorUniversity of Maryland, BaltimoreEnrollment2Endometrial Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

A phase 2 study with the primary objective of testing treatment compliance of Upfront Intensity Modulated Proton Beam Therapy (IMPT) and Concurrent Chemotherapy (UPPROACH) for Post-operative Treatment in Loco-regionally Advanced Endometrial Cancer is non-inferior to the historic compliance rate of the chemoradiation arm of GOG 258 study

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

  • Pranshu Mohindra, MD

    University of Maryland/Maryland Proton Treatment Center

    Principal Investigator

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

4 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Maryland Proton Treatment Center

    Baltimore, Maryland, United States

  • Ummc

    Baltimore, Maryland, United States

  • Central Maryland Radiation Oncology

    Columbia, Maryland, United States

  • Baltimore Washington Medical Center

    Glen Burnie, Maryland, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Carboplatin and paclitaxel
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
23 Feb 2021
Primary completion
2 Jul 2024
Completion
2 Jul 2024
Last update posted
8 Jul 2026
Registered enrollment
2
Registry id
NCT04527900

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.