Clinical trialNCT04551911CompletedPhase 2Interventional

Safety and Efficacy of Rayaldee for Treating Mild to Moderate COVID-19

SponsorOPKO Health, Inc.Enrollment171COVID-19CoronavirusSARS-CoV2 Infection

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a phase 2, single or multi-center, randomized, double-blind placebo-controlled study to evaluate the safety and efficacy of Rayaldee (CTAP101 Capsules) to treat adult subjects with mild to moderate COVID-19 who test positive for SARS-CoV-2.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Akhtar Ashfaq, MD FACP FASN
OPKO Health, Inc.
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Opko Investigative Site
San Francisco, California, United States
Opko Investigative Site
Miami, Florida, United States
Opko Investigative Site
Miami, Florida, United States
Opko Investigative Site
Evanston, Illinois, United States
Opko Investigative Site
Laurel, Maryland, United States
Opko Investigative Site
Farmington Hills, Michigan, United States
Opko Investigative Site
Jackson, Michigan, United States
Opko Investigative Site
Sterling Heights, Michigan, United States
Opko Investigative Site
Brookhaven, Mississippi, United States
Opko Investigative Site
Omaha, Nebraska, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboCalcifediol →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 2 Nov 2020
Primary completion: 8 Oct 2021
Completion: 8 Oct 2021
Last update posted: 28 May 2024
Registered enrollment: 171
Registry id: NCT04551911

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.