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Clinical trialNCT04553770RecruitingPhase 2Interventional

Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer

SponsorJonsson Comprehensive Cancer CenterEnrollment88Early-stage Breast CancerHormone Receptor Positive Breast CarcinomaInvasive Breast CancerStage II Breast CancerStage IIA Breast CancerStage IIB Breast Cancer+1 more conditions
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • St. Joseph Heritage Healthcare

    Fullerton, California, United States

    William E. Lawler, M.D.
    Recruiting
  • Cancer Blood and Specialty Clinic

    Los Alamitos, California, United States

    Vu Phan, M.D.
    Recruiting
  • Ucla / Jonsson Comprehensive Cancer Center

    Los Angeles, California, United States

    Nicholas P McAndrew, M.D.
    Recruiting
  • Torrance Memorial Physician Network / Cancer Care

    Torrance, California, United States

    David Chan, M.D.
    Recruiting
  • Pih Health

    Whittier, California, United States

    Lisa Shing-E Lu Wang, M.D.
    Recruiting
  • Orlando Health, Inc. D/b/a Orlando Health Uf Health Center

    Orlando, Florida, United States

    Withdrawn
  • Ft. Wayne Medical Oncology and Hematology, Inc.

    Fort Wayne, Indiana, United States

    Withdrawn
  • Cancer Center of Kansas

    Wichita, Kansas, United States

    Shaker Dakhil, M.D.
    Recruiting
  • Massachusetts General Hospital

    Boston, Massachusetts, United States

    Laura M Spring, M.D.
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
9 Oct 2020
Primary completion
31 Dec 2026
Completion
31 Dec 2026
Last update posted
10 Nov 2025
Registered enrollment
88
Registry id
NCT04553770

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.