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Clinical trialNCT04562389Active, not recruitingPhase 3Interventional

Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis

SponsorKaryopharm Therapeutics IncEnrollment353Myelofibrosis
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

166 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Bankstown-Lidcombe Hospital

    Bankstown, New South Wales, Australia

  • Campbelltown Hospital

    Campbelltown, New South Wales, Australia

  • Liverpool Hospital

    Liverpool, New South Wales, Australia

  • Icon Cancer Centre - Wesley

    South Brisbane, Queensland, Australia

  • Royal Adelaide Hospital

    Adelaide, South Australia, Australia

  • One Clinical Research

    Nedlands, Western Australia, Australia

Belgium
  • Universitair Ziekenhuis Leuven - Campus Gasthuisberg

    Leuven, Flemish Brabant, Belgium

  • Universitair Ziekenhuis Gent

    Ghent, Oost-Vlaanderen, Belgium

  • Algemeen Ziekenhuis Sint-Jan Brugge-Oostende - Campus Sint-Jan

    Bruges, West-Vlaanderen, Belgium

  • Zna Stuivenberg

    Antwerp, Belgium

  • Zna Stuivenberg - Satelite

    Antwerp, Belgium

Bulgaria
  • University Multiprofile Hospital for Active Treatment Sveti George - Base 1

    Plovdiv, Bulgaria

  • Specialized Hospital for Active Treatment of Hematological Diseases - Ead Sofia

    Sofia, Bulgaria

  • University Multiprofile Hospital for Active Treatment Aleksandrovska

    Sofia, Bulgaria

  • University Multiprofile Hospital for Active Treatment St. Ivan Rilski

    Sofia, Bulgaria

  • University Multiprofile Hospital for Active Treatment - Prof. Dr. Stoyan Kirkovich

    Stara Zagora, Bulgaria

Canada
  • University of Alberta Hospital

    Edmonton, Alberta, Canada

  • Lakeridge Health

    Oshawa, Ontario, Canada

  • Research Institute of the Mcgill University Health Centre

    Montreal, Quebec, Canada

Czechia
  • Vseobecna Fakultni Nemocnice V Praze

    Prague, Prague, Czechia

  • Fakultní Nemocnice Hradec Králové

    Hradec Králové, Czechia

  • Fakultní Nemocnice Olomouc

    Olomouc, Czechia

Denmark
  • Aarhus Universitetshospital

    Aarhus N, Central Jutland, Denmark

  • Tang Severinsen, Marianne

    Aalborg, North Denmark, Denmark

France
  • Institut Bergonié

    Bordeaux, Aquitaine, France

  • Centre Hospitalier Universitaire Estaing

    Clermont-Ferrand, Aubergne, France

  • Centre Hospitalier Lyon-Sud

    Pierre-Bénite, Auvergne-Rhône-Alpes, France

  • Hôpital Morvan

    Brest, Brittany Region, France

  • Chu de Nîmes - Institut de Cancérologie Du Gard

    Nîmes, Gard, France

  • Hôpital Emile Muller

    Mulhouse, Grand Est, France

  • Hôpital Huriez

    Lille, Hauts-de-France, France

  • Hôpital Bretonneau

    Tours, Indre-et-Loire, France

  • Hôpital L'Archet - Chu Nice

    Nice, PACA, France

  • Centre Hospitalier Universitaire D'Angers

    Angers, Pays de la Loire Region, France

  • Centre Hospitalier Universitaire de Saint-Étienne

    Saint-Priest-en-Jarez, Pays de la Loire Region, France

  • Hôpital Cochin

    Paris, Île-de-France Region, France

  • Hôpital Universitaire Pitié Salpêtrière

    Paris, Île-de-France Region, France

  • Hôpital Saint-Louis

    Paris, France

Germany
  • Kliniken Ostalb - Stauferklinikum Schwäbisch Gmünd

    Mutlangen, Baden-Wurttemberg, Germany

  • Marien Hospital Düsseldorf

    Düsseldorf, North Rhine-Westphalia, Germany

126 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
11 Mar 2021
Primary completion
20 Feb 2026
Completion
31 Mar 2028
Last update posted
9 Apr 2026
Registered enrollment
353
Registry id
NCT04562389

Cross-registrations

EU-CTR / CTIS (EudraCT)2020-003883-19EU-CTR / CTIS (EudraCT)2023-506139-13-00

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.