A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment
Summary
The lay summary the sponsor registered on ClinicalTrials.gov.
Investigators
The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.
- Joe Eid
Geron Corporation
Study Director
A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.
Sites
144 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.
- Hospital Aleman
Ciudad de Buenos Aires, Buenos Aires, Argentina
- Sanatorio de la Mujer
Rosario, Santa Fe Province, Argentina
- Sanatorio Allende
Córdoba, Argentina
- Royal North Shore Hospital
St Leonards, New South Wales, Australia
- Royal Brisbane and Women'S Hospital
Herston, Queensland, Australia
- Royal Hobart Hospital
Hobart, Tasmania, Australia
- Epworth Healthcare
Richmond, Victoria, Australia
- Krankenhaus Hietzing Mit Neurologischem Zentrum Rosenhügel
Wein, Burgenland, Austria
- Kepler Universitätsklinikum Gm
Linz, Upper Austria, Austria
- Krankenhaus Der Elisabethinen
Linz, Upper Austria, Austria
- Klinikum Wels-Grieskirchen Gmbh
Wels, Upper Austria, Austria
- Az Klina
Antwerp, Antwerpen, Belgium
- Uz Antwerpen
Edegem, Antwerpen, Belgium
- Centre Hospitalier de Jolimont
Haine-Saint-Paul, Hainaut, Belgium
- Universitair Ziekenhuis Gent
Ghent, Oost-Vlaanderen, Belgium
- Universitair Ziekenhuis Brussel - Myeloom Centrum Brussel (mcb)
Jette, Belgium
- Centro de Oncologia Leonardo Da Vinci
Fortaleza, Ceará, Brazil
- Hospital Das Clínicas Ufg
Goiânia, Goiás, Brazil
- Hospital Erasto Gaertner
Curitiba, Paraná, Brazil
- Centro Gaucho Integrado de Oncologia, Hematologia, Ensino E Pesquisa Ltda
Porto Alegre, Rio Grande do Sul, Brazil
- Hospital de Clinicas de Porto Alegre - Ufrgs
Porto Alegre, Rio Grande do Sul, Brazil
- Fundacao Doutor Amaral Carvalho / Hospital Amaral Carvalho
São Paulo, São Paulo, Brazil
- Hospital Israelita Albert Einstein
São Paulo, São Paulo, Brazil
- Cepon Centro de Pesquisas Oncologicas Sc
Florianópolis, Brazil
- Hospital A.C.Camargo Cancer Center - Clinical Oncology
São Paulo, Brazil
- Umbal Sveti Georgi
Plovdiv, Plovdiv, Bulgaria
- Specialized Hospital for Active Therapy of Hematological Dis
Sofia, Sofia, Bulgaria
- Oncologos del Occidente S.A
Pereira, Risaralda Department, Colombia
- Hospital Pablo Tobon Uribe
Antioquia, Colombia
- Odense University Hospital - Hematology
Odense, Denmark
- Centre Hospitalier Lyon
Pierre-Bénite, Auvergne-Rhône-Alpes, France
- Chu Bretonneau
Tours, Indre-et-Loire, France
- Hopital Bicetre
Paris, Le Kremlin-Bicêtre, France
- Chu de Nantes - Hematologie
Nantes, Loire-Atlantique, France
- Chu de Nice - Hopital de L'Archet Ii - Pharmacie
Nice, Nice Cedex 3, France
- Centre Hospitalier Du Mans - Cancérologie Médicale
Le Mans, Sarthe, France
- Chru Brest - Hôpital Morvan
Brest, France
- Chu - Hã´pital Saint Louis - Centre D'Investigations Cliniq
Paris, France
- J.S.C."k.Eristavi National Cen
Tbilisi, K'alak'i T'bilisi, Georgia
- Ltd "medinvest - Institute of Hematology and Trans
Tbilisi, K'alak'i T'bilisi, Georgia
Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.
Drugs studied
The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.
Registration & key dates
Registry attributes as recorded on the ClinicalTrials.gov study record.
- Start
- 12 Apr 2021
- Primary completion
- 30 Jun 2028
- Completion
- 30 Jun 2028
- Last update posted
- 8 Jul 2026
- Registered enrollment
- 327
- Registry id
- NCT04576156
Cross-registrations
Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.