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Clinical trialNCT04625725CompletedPhase 3Interventional

Phase III Double-blind, Placebo-controlled Study of AZD7442 for Pre-exposure Prophylaxis of COVID-19 in Adult.

SponsorAstraZenecaEnrollment5,197COVID-19
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study will assess the safety and efficacy of a single dose of AZD7442(× 2 IM injections) compared to placebo for the prevention of COVID-19.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

89 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Belgium
  • Research Site

    Alken, Belgium

  • Research Site

    Brussels, Belgium

  • Research Site

    Gozée, Belgium

  • Research Site

    Namur, Belgium

  • Research Site

    Wetteren, Belgium

France
  • Research Site

    Clermont-Ferrand, France

  • Research Site

    Dijon, France

  • Research Site

    La Roche S/ Yon Cedex 9, France

  • Research Site

    Lille, France

  • Research Site

    Limoges, France

  • Research Site

    Nantes, France

  • Research Site

    Paris, France

  • Research Site

    Paris, France

  • Research Site

    Saint-Etienne, France

  • Research Site

    Tours, France

Spain
  • Research Site

    Barcelona, Spain

  • Research Site

    Madrid, Spain

  • Research Site

    Madrid, Spain

  • Research Site

    Marbella (Málaga), Spain

  • Research Site

    Pozuelo de Alarcón, Spain

United Kingdom
  • Research Site

    Bournemouth, United Kingdom

  • Research Site

    Enfield, United Kingdom

  • Research Site

    Hayle, United Kingdom

  • Research Site

    London, United Kingdom

  • Research Site

    Preston, United Kingdom

  • Research Site

    Rochdale, United Kingdom

  • Research Site

    Salford, United Kingdom

  • Research Site

    Torpoint, United Kingdom

  • Research Site

    Wakefield, United Kingdom

United States
  • Research Site

    Birmingham, Alabama, United States

  • Research Site

    Tempe, Arizona, United States

  • Research Site

    Little Rock, Arkansas, United States

  • Research Site

    Cerritos, California, United States

  • Research Site

    Fresno, California, United States

  • Research Site

    Garden Grove, California, United States

  • Research Site

    Huntington Beach, California, United States

  • Research Site

    Lancaster, California, United States

  • Research Site

    Modesto, California, United States

  • Research Site

    Victorville, California, United States

  • Research Site

    Westminster, California, United States

49 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

AZD7442Placebo
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
21 Nov 2020
Primary completion
16 Aug 2022
Completion
8 Dec 2023
Last update posted
31 Dec 2024
Registered enrollment
5,197
Registry id
NCT04625725

Cross-registrations

EU-CTR / CTIS (EudraCT)2020-004356-16
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.