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Clinical trialNCT04640025TerminatedPhase 2Interventional

A Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Itacitinib

SponsorIncyte CorporationEnrollment18Chronic Graft Versus Host DiseaseMyelofibrosisPostlung Transplant (Bronchiolitis Obliterans)
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a mutli-center open-label study to provide continued supply of itacitinib to participants from the following Incyte-sponsored studies of itacitinib: INCB39110-209, INCB39110-213, INCB39110-214, INCB39110-230, and 39110-309. Eligible participants will receive treatment with itacitinib as per the treatment dose and schedule they received in the study in which they were originally enrolled. The original study is referred to as the "parent protocol". Participants who receive itacitinib in this study may continue treatment as long as the regimen is tolerated, the participant is deriving clinical benefit (in the opinion of the investigator), and the participant does not meet discontinuation criteria.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

21 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Austria
  • Ordensklinikum Linz Gmbh Elisabethinen

    Linz, Austria

Belgium
  • Universitaire Ziekenhuis Leuven - Gasthuisberg

    Leuven, Belgium

Canada
  • Providence Health

    Vancouver, British Columbia, Canada

Germany
  • Universitatsklinikum Halle (saale)

    Halle, Germany

  • University Medical Centre Hamburg-Eppendorf Centre of Oncology

    Hamburg, Germany

  • University Hospital Mannheim

    Mannheim, Germany

Greece
  • University Hospital of West Attica - Attikon

    Chaïdári, Greece

Israel
  • Hadassah Hebrew University Medical Center Ein Karem Hadassah

    Jerusalem, Israel

Italy
  • Azienda Policlinico Vittorio Emanuele

    Catania, Italy

  • Azienda Ospedaliera Bianchi-Melacrino-Morelli Ospedali Riuniti

    Reggio Calabria, Italy

  • Aou San Giovanni Di Dio E Ruggi

    Salerno, Italy

Spain
  • Hospital Universitario Virgen de Las Nieves

    Granada, Spain

  • Hospital Universitario Ramon Y Cajal

    Madrid, Spain

United States
  • City of Hope National Medical Center

    Duarte, California, United States

  • Anschutz Cancer Pavilion-University of Colorado

    Aurora, Colorado, United States

  • Parkview Cancer Institute

    Fort Wayne, Indiana, United States

  • Cleveland Clinic

    Cleveland, Ohio, United States

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, United States

  • Temple University Department of Thoracic Medicine and Surgery

    Philadelphia, Pennsylvania, United States

  • Sarah Cannon Research Institute

    Nashville, Tennessee, United States

  • Texas Oncology San Antonio

    San Antonio, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Itacitinib
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
10 Mar 2021
Primary completion
11 May 2026
Completion
11 May 2026
Last update posted
26 Jun 2026
Registered enrollment
18
Registry id
NCT04640025

Cross-registrations

EU-CTR / CTIS (EudraCT)2020-002134-32EU-CTR / CTIS (EudraCT)2022-501661-47-00

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.