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Clinical trialNCT04644211RecruitingPhase 2Interventional

Ruxolitinib in Thrombocythemia and Polycythemia Vera

SponsorMassachusetts General HospitalEnrollment60Essential ThrombocythemiaPolycythemia Vera
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This research is being done to see if the drug ruxolitinib is effective in reducing the symptoms caused by low-risk essential thrombocythemia (ET) and polycythemia vera (PV). \- This research study involves the study drug Ruxolitinib.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

4 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Beth-Israel Deaconess Medical Center

    Boston, Massachusetts, United States

    Jeffrey Zwicker, MD
    Not, yet, recruiting
  • Dana Farber Cancer Institute

    Boston, Massachusetts, United States

    Marlise Luskin, MD
    Recruiting
  • Massachusetts General Hospital

    Boston, Massachusetts, United States

    Gabriela Hobbs, MD
    Recruiting
  • Massachusetts General North Shore Cancer Center

    Danvers, Massachusetts, United States

    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Ruxolitinib →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
21 Mar 2022
Primary completion
31 Jul 2027
Completion
31 Jul 2034
Last update posted
8 Jan 2026
Registered enrollment
60
Registry id
NCT04644211
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.