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Clinical trialNCT04663802CompletedInterventional

Implementation of Nudges to Promote Utilization of Low Tidal Volume Ventilation (INPUT) Study

SponsorUniversity of PennsylvaniaEnrollment7,342ARDSAcute Respiratory Distress SyndromeAcute Respiratory FailureCritical Illness
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study is a large pragmatic stepped-wedge trial of electronic health record (EHR)-based implementation strategies informed by behavioral economic principles to increase lung-protective ventilation (LPV) utilization among all mechanically ventilated (MV), adult patients. The study will compare the standard approach to managing MV across 12 study Intensive Care Units (ICUs) within University of Pennsylvania Health System (UPHS) versus interventions prompting physicians and respiratory therapists (RTs) to employ LPV settings promote LPV utilization among all MV patients.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Princeton Medical Center

    Plainsboro, New Jersey, United States

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, United States

  • Penn Presbyterian Medical Center

    Philadelphia, Pennsylvania, United States

  • Pennsylvania Hospital

    Philadelphia, Pennsylvania, United States

  • Chester County Hospital

    West Chester, Pennsylvania, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
22 Feb 2021
Primary completion
15 Jun 2023
Completion
15 Dec 2023
Last update posted
8 Oct 2024
Registered enrollment
7,342
Registry id
NCT04663802
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.