Clinical trialNCT04685135Active, not recruitingPhase 3Interventional

Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation

SponsorMirati Therapeutics Inc.Enrollment453Advanced Non Small Cell Lung CancerMetastatic Non Small Cell Lung Cancer

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Bristol-Myers Squibb
Bristol-Myers Squibb
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

343 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia

Local Institution - 012-016
Mackay, Queensland, Australia
Local Institution - 012-005
Bedford Park, Australia
Local Institution - 012-004
Clayton, Australia
Townsville University Hospital
Douglas, Australia
Local Institution - 012-013
St Leonards, Australia
Local Institution - 012-019
Tweed Heads, Australia
Cancer Care Wollongong
Wollongong, Australia
Princess Alexandra Hospital
Woolloongabba, Australia

Austria

Klinikum Klagenfurt Am Worthersee
Klagenfurt, Austria
Uniklinikum Salzburg
Salzburg, Austria
Wiener Gesundheitsverbund - Klinik Ottakring
Vienna, Austria

Belgium

Universitair Ziekenhuis Brussel
Brussels, Belgium
Local Institution - 012-157
Edegem, Belgium
Local Institution - 012-155
Ghent, Belgium
Local Institution - 012-151
Gilly, Belgium
Local Institution - 012-158
Hasselt, Belgium
Local Institution - 012-152
Roeselare, Belgium
Algemeen Ziekenhuis Glorieux Ronse
Ronse, Belgium
Local Institution - 012-150
Yvoir, Belgium

Czechia

Local Institution - 012-164
Hořovice, Czechia
Local Institution - 012-162
Olomouc, Czechia
Vseobecna Fakultni Nemocnice V Praze
Prague, Czechia
Fakultni Nemocnice Bulovka
Praha 8 - Liben, Czechia

France

Local Institution - 012-191-A
Pierre-Bénite, Auvergne-Rhône-Alpes, France
Local Institution - 012-191-B
Lyon, Rhone, France
Local Institution - 012-194
Brest, France
Hopital Louis Pradel
Bron, France
Local Institution - 012-193
Caen, France
Local Institution - 012-196
Caen, France
Centre Hospitalier Intercommunal de Creteil
Créteil, France
Local Institution - 012-192
Dijon, France
Lhopital Nord-Ouest (hno) - Villefranche-Sur-Saone
Gleizé, France
Hopital Michallon
La Tronche, France
Centre Hospitalier Regional Universitaire de Lille
Lille, France
Centre Hospitalier Universitaire Dupuytren 1
Limoges, France
Hopital Nord de Marseille
Marseille, France
Institut Paoli-Calmettes
Marseille, France
Hopital Arnaud de Villeneuve
Montpellier, France
Hopital Emile Muller
Mulhouse, France
Local Institution - 012-685
Nice, France

303 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 23 Feb 2021
Primary completion: 30 Dec 2023
Completion: 2 Jul 2026
Last update posted: 22 Jan 2025
Registered enrollment: 453
Registry id: NCT04685135

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.