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Clinical trialNCT04730258Active, not recruitingPhase 1/PHASE2Interventional

A Study of CFI-400945 With or Without Azacitidine in Patients With AML, MDS or CMML

SponsorTreadwell Therapeutics, IncEnrollment72AMLAcute Myeloid LeukemiaCMMLChronic Myelomonocytic LeukemiaMDSMyelodysplastic Syndromes
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • University of Alberta

    Edmonton, Alberta, Canada

  • Princess Margaret Cancer Center

    Toronto, Ontario, Canada

Hong Kong
  • Queen Mary Hospital

    Hong Kong, Hong Kong

United States
  • City of Hope

    Duarte, California, United States

  • University of California Davis Comprehensive Cancer Center

    Sacramento, California, United States

  • Norton Cancer Institute - Saint Matthews

    Louisville, Kentucky, United States

  • New York Presbyterian Weill Cornell Medical Center

    New York, New York, United States

  • the Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, United States

  • the University of Texas Md Anderson Cancer Centre

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Azacitidine →Ocifisertib Fumarate
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
16 Apr 2021
Primary completion
31 Jan 2026
Completion
31 Jan 2026
Last update posted
18 May 2025
Registered enrollment
72
Registry id
NCT04730258
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.