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Clinical trialNCT04747093UnknownPhase 1/PHASE2Interventional

Induced-T Cell Like NK Cells for B Cell Malignancies

SponsorNanfang Hospital, Southern Medical UniversityEnrollment12B Cell LeukemiaB Cell LymphomaB-cell Acute Lymphoblastic LeukemiaB-cell Lymphoma RecurrentB-cell Lymphoma Refractory
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Relapsed and refractory B cell malignancies show unfavorable prognosis, especially for adult patients. Now, there is no standard management for these patients. Induced-T cell-like NK cells with chimeric antigen receptor (CAR-ITNK cells) is a promising treatment option for treating B cell derived malignancy. The purpose of this study is to evaluate the efficacy and safety of CAR-ITNK cells infusions in patients with relapsed and refractory B cell malignancies.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

China
  • Department of Hematology,nanfang Hospital, Southern Medical University

    Guangzhou, Guangdong, China

    Qifa Liu
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

CAR-ITNK cells
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
29 Jan 2021
Primary completion
31 Dec 2021
Completion
31 Mar 2022
Last update posted
10 Feb 2021
Registered enrollment
12
Registry id
NCT04747093

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.