Clinical trialNCT04752228UnknownInterventional

Adverse Childhood Experiences in Patients With Coronary Artery Disease Pilot

SponsorUniversity Health Network, TorontoEnrollment100Adverse Childhood ExperiencesCoronary Artery Disease

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Adverse Childhood Experiences (ACEs) are potentially harmful events occurring during childhood that have been associated with chronic physical conditions in adulthood, including coronary artery disease (CAD). ACEs may constitute a portion of the remaining unexplained residual risk for CAD in adults. Identifying a means of addressing these experiences may mitigate their health consequences and result in improved cardiovascular outcomes. The primary objective of this study is to determine if patients who undergo ACE screening experience improved quality of life compared to patients who undergo conventional lifestyle assessment. This will be a single-centre, pragmatic, single-blinded (i.e. data analysts), 1:1, pilot randomized control trial.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Christine Lay, MD
Women's College Hospital, Canada
Principal Investigator
clinicaltrials.gov ↗
Claudia Frankfurter, MD
University Health Network-Toronto General Hospital, Canada
Principal Investigator
clinicaltrials.gov ↗
Lucas C Godoy, MD
University Health Network-Toronto General Hospital, Canada
Principal Investigator
clinicaltrials.gov ↗
Michael Farkouh, MD
University Health Network-Toronto General Hospital, Canada
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗
Robert Maunder, MD
Mount Sinai Hospital, Canada
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Peter Munk Cardiac Centre - University Health Network
Toronto, Canada
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Sept 2021
Primary completion: 31 Dec 2022
Completion: 30 Jun 2023
Last update posted: 31 May 2022
Registered enrollment: 100
Registry id: NCT04752228

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.