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Clinical trialNCT04762225TerminatedPhase 1Interventional

RPTR-168 in Patients With Human Papillomavirus Strain 16 (HPV-16) E6/E7 Positive Tumors and Melanoma

SponsorRepertoire Immune MedicinesEnrollment7Cervical CancerHead and Neck Squamous Cell CarcinomaMelanoma
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to assess the safety and tolerability of escalating doses of RPTR-168 as a monotherapy in patients with HPV-16 E6/E7 positive tumors (HNSCC, cervical) and melanoma.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

4 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Honorhealth Research Institute

    Scottsdale, Arizona, United States

  • Usc Norris Comprehensive Cancer Center

    Los Angeles, California, United States

  • University of Michigan Comprehensive Cancer Center

    Ann Arbor, Michigan, United States

  • Carolina Biooncology Institute

    Huntersville, North Carolina, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

RPTR-168
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
10 May 2021
Primary completion
14 Sept 2022
Completion
11 Oct 2022
Last update posted
6 Dec 2022
Registered enrollment
7
Registry id
NCT04762225
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.