Clinical trialNCT04834414CompletedPhase 3Interventional

CHIlled Platelet Study "CHIPS"

SponsorPhilip SpinellaEnrollment1,000Acute Blood Loss

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

A phase 3 randomized partial blind storage duration ranging study in patients undergoing complex cardiac surgery that will compare the transfusion of cold stored platelets to standard room temperature stored platelets. The primary objective is to establish that cold stored platelets have a non-inferiority (or superiority) to room temperature platelets.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Marie E Steiner, MD
University of Minnesota
Study Director
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Nicole D Zantek, MD
University of Minnesota
Study Director
clinicaltrials.gov ↗
Philip C Spinella, MD
University of Pittsburgh
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

27 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia

Fiona Stanley Hospital
Murdoch, Western Australia, Australia
Sir Charles Gairdner Hospital
Nedlands, Western Australia, Australia

United States

Mayo Clinic Arizona
Phoenix, Arizona, United States
Banner University Medical Center
Tucson, Arizona, United States
Ronald Reagan Ucla Medical Center
Los Angeles, California, United States
University of Florida
Gainesville, Florida, United States
Northwestern Memorial Hospital
Chicago, Illinois, United States
Loyola Universtiy Medical Center
Maywood, Illinois, United States
University of Kansas Medical Center
Kansas City, Kansas, United States
University of Kentucky
Lexington, Kentucky, United States
John Hopkins
Baltimore, Maryland, United States
University of Michigan
Ann Arbor, Michigan, United States
University of Minnesota
Minneapolis, Minnesota, United States
Mayo Clinic
Rochester, Minnesota, United States
Wake Forest
Winston-Salem, North Carolina, United States
Cincinnati Children'S Hospital
Cincinnati, Ohio, United States
Oregon Health and Science University
Portland, Oregon, United States
Children'S Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States
Rhode Island Hospital
Providence, Rhode Island, United States
University of Texas Children'S Medical Center
Dallas, Texas, United States
University of Texas Medical Center Clements
Dallas, Texas, United States
Baylor Texas Children'S
Houston, Texas, United States
Memorial Hermann Texas Medical Center
Houston, Texas, United States
University of Wisconsin- Madison
Madison, Wisconsin, United States
Aurora St. Luke'S Medical Center
Milwaukee, Wisconsin, United States
Children'S Hospital of Wisconsin
Milwaukee, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Cold Stored PlateletsRoom Temperature Platelets

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 21 Oct 2021
Primary completion: 25 Mar 2025
Completion: 21 Apr 2025
Last update posted: 11 Jul 2025
Registered enrollment: 1,000
Registry id: NCT04834414

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.