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Clinical trialNCT04849988CompletedPhase 2Interventional

A Phase 2 Study to Evaluate the Safety and Efficacy of ABP-450 in the Treatment of Cervical Dystonia

SponsorAEON Biopharma, Inc.Enrollment61Cervical Dystonia
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This Phase 2 trial will evaluate the safety and efficacy of ABP-450 for the treatment of cervical dystonia in adults. The study will enroll 60 patients across approximately 30 sites in the United States. Study subjects will be divided evenly across a low dose group, a medium dose group, a high dose group, and a placebo group for one treatment cycle.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

21 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Arizona Neuroscience Research

    Phoenix, Arizona, United States

  • Movement Disorder Center of Arizona

    Scottsdale, Arizona, United States

  • Parkinson'S and Movement Disorder Institute

    Fountain Valley, California, United States

  • Neuro Pain Medical Center

    Fresno, California, United States

  • Loma Linda University

    Loma Linda, California, United States

  • New England Institute for Neurology and Headache

    Stamford, Connecticut, United States

  • Infinity Clinical Research Llc

    Hollywood, Florida, United States

  • the Neurology Research Group

    Miami, Florida, United States

  • University of South Florida

    Tampa, Florida, United States

  • Neurology One

    Winter Park, Florida, United States

  • Emory University

    Atlanta, Georgia, United States

  • Rush University Medical Center

    Chicago, Illinois, United States

  • Michigan State University

    East Lansing, Michigan, United States

  • Quest Research Institute - Hunt - Ppds

    Farmington Hills, Michigan, United States

  • University of New Mexico

    Albuquerque, New Mexico, United States

  • Cleveland Clinic Lou Ruvo Center for Brain Health

    Cleveland, Ohio, United States

  • the Cleveland Clinic Foundation

    Cleveland, Ohio, United States

  • the Orthopedic Foundation

    New Albany, Ohio, United States

  • Veracity Neuroscience Llc

    Memphis, Tennessee, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, United States

  • Baylor College of Medicine

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

ABP-450Placebo
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
29 Mar 2021
Primary completion
11 Jul 2022
Completion
11 Jul 2022
Last update posted
14 Feb 2024
Registered enrollment
61
Registry id
NCT04849988

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.