Clinical trialNCT04852887RecruitingPhase 3Interventional

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

SponsorNRG OncologyEnrollment1,670Stage I Breast Cancer

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

832 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Atlantic Health Sciences Corporation-Saint John Regional Hospital
Saint John, New Brunswick, Canada
Farah Naz
Recruiting
Kingston Health Sciences Centre
Kingston, Ontario, Canada
Timothy Owen
Recruiting
Odette Cancer Centre- Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
Eileen Rakovitch
Recruiting
Chum - Centre Hospitalier de L'Universite de Montreal
Montreal, Quebec, Canada
Jean-Marc Bourque
Recruiting
Chu de Quebec-L'Hotel-Dieu de Quebec (hdq)
Québec, Quebec, Canada
Valerie Theberge
Recruiting
Allan Blair Cancer Centre
Regina, Saskatchewan, Canada
Derek Suderman
Recruiting
Saskatoon Cancer Centre
Saskatoon, Saskatchewan, Canada
Ali A. El-Gayed
Recruiting

Hong Kong

Pamela Youde Nethersole Eastern Hospital
Chai Wan, Hong Kong
Suspended

Japan

Ehime University Hospital
Tōon, Ehime, Japan
Yoshiaki Kamei
Recruiting
Hokkaido University Hospital
Sapporo, Hokkaido, Japan
Masato Takahashi
Recruiting
Hyogo Cancer Center
Akashi, Hyōgo, Japan
Koji Matsumoto
Recruiting
Gunma University Hospital
Gunma, Maebashi, Japan
Sasagu Kurozumi
Recruiting
the Cancer Institute Hospital of Jfcr
Koto-ku, Tokyo, Japan
Takehiko Sakai
Recruiting
Hiroshima University Hospital
Hiroshima, Japan
Hideo Shigematsu
Recruiting
Kyoto University Hospital
Kyoto, Japan
Norikazu Masuda
Recruiting
Shikoku Cancer Center
Matsuyama, Japan
Daisuke Takabatake
Recruiting
Nagoya University Hospital
Nagoya, Japan
Yuko Takano
Recruiting
Kindai University
Osaka, Japan
Yoshifumi Komoike
Recruiting
Saitama Medical University International Medical Center
Saitama, Japan
Akihiro Fujimoto
Recruiting
National Cancer Center Hospital
Tokyo, Japan
Shin Takayama
Recruiting

United States

University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, United States
Active, not recruiting
University of South Alabama Mitchell Cancer Institute
Mobile, Alabama, United States
Ayesha Munir
Recruiting
Kingman Regional Medical Center
Kingman, Arizona, United States
John A. Ellerton
Recruiting
Cancer Center at Saint Joseph'S
Phoenix, Arizona, United States
Shahzad Siddique
Recruiting
Mayo Clinic Hospital in Arizona
Phoenix, Arizona, United States
Active, not recruiting
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States
Sanjay Maraboyina
Recruiting
Kaiser Permanente-Anaheim
Anaheim, California, United States
Aakash Batra
Recruiting
Kaiser Permanente-Deer Valley Medical Center
Antioch, California, United States
Samantha A. Seaward
Recruiting
Mission Hope Medical Oncology - Arroyo Grande
Arroyo Grande, California, United States
Shahzad Siddique
Recruiting
Pcr Oncology
Arroyo Grande, California, United States
John A. Ellerton
Recruiting
Sutter Auburn Faith Hospital
Auburn, California, United States
Kristie A. Bobolis
Recruiting
Sutter Cancer Centers Radiation Oncology Services-Auburn
Auburn, California, United States
Kristie A. Bobolis
Recruiting
Kaiser Permanente-Bellflower
Bellflower, California, United States
Aakash Batra
Recruiting
Alta Bates Summit Medical Center-Herrick Campus
Berkeley, California, United States
Kristie A. Bobolis
Recruiting
Tower Cancer Research Foundation
Beverly Hills, California, United States
Suspended
Mercy Cancer Center - Carmichael
Carmichael, California, United States
Shahzad Siddique
Recruiting
Mercy San Juan Medical Center
Carmichael, California, United States
Matthew D. Wheatley
Recruiting
Epic Care-Dublin
Dublin, California, United States
Active, not recruiting
Kaiser Permanente Dublin
Dublin, California, United States
Samantha A. Seaward
Recruiting
Mercy Cancer Center - Elk Grove
Elk Grove, California, United States
Shahzad Siddique
Recruiting

792 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 23 Jun 2021
Primary completion: 8 Apr 2031
Completion: 31 Jul 2041
Last update posted: 23 Apr 2026
Registered enrollment: 1,670
Registry id: NCT04852887

Cross-registrations

Other registry (CTRPNCI-2021-00222

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.