Clinical trialNCT04855526Not, yet, recruitingEarly phase 1Interventional

THC + CBD and Memory Study

SponsorHartford HospitalEnrollment9Cannabis IntoxicationCannabis UseMarijuana Use

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Memory deficits are one of the most consistently observed cognitive effects of marijuana use. There is evidence that some decrements attributable to the primary psychoactive ingredient, delta-9-tetrahydrocannabinol (THC), may be attenuated by cannabidiol (CBD). This study will help us learn more about the relationship between THC and CBD consumption with memory processes. A combination of MRI and neuropsychological tests (which are computer and paper/pencil tasks) will be used to measure the neurocognitive and behavioral impacts of THC and CBD use.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Alecia Dager, PhD
Hartford Hospital - Olin Neuropsychiatry Research Center; Yale University
Principal Investigator
clinicaltrials.gov ↗
Godfrey Pearlson, MD
Hartford Hospital - Olin Neuropsychiatry Research Center; Yale University
Principal Investigator
clinicaltrials.gov ↗
Michael Stevens, PhD
Hartford Hospital - Olin Neuropsychiatry Research Center
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

No facility list is in our current data snapshot for this study. The registry record on ClinicalTrials.gov ↗ carries any published locations. Why? →

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

High THC/High CBD MarihuanaHigh THC/No CBD MarihuanaNo THC/No CBD Marihuana

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Dec 2025
Primary completion: 30 Dec 2026
Completion: 30 Dec 2026
Last update posted: 17 Mar 2025
Registered enrollment: 9
Registry id: NCT04855526

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.