Clinical trialNCT04959097RecruitingObservational

Retinoblastoma Patient Clinical Database and Tissue Repository

SponsorChildren's Hospital Los AngelesEnrollment800RetinoblastomaRetinoblastoma BilateralRetinoblastoma Unilateral

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Retinoblastoma (RB) is a primary eye cancer that forms in the back of the eye of infants and toddlers. Traditionally, RB is diagnosed without a biopsy; tumor can only be studied once an eye has been surgically removed. Given this limitation, we use aqueous humor (AH), the clear fluid in the front of the eye to detect specific markers, or information, that comes from the tumor itself.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Jesse L Berry, MD
Children's Hospital Los Angeles
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

the Hospital for Sick Children (toronto Sickkids)
Toronto, Ontario, Canada
Brenda Gallie, MD, FRCSC, CM, OOnt
Recruiting

United States

Phoenix Children'S Hospital
Phoenix, Arizona, United States
Merrylees Dersch, MD
Recruiting
Children'S Hospital Los Angeles
Los Angeles, California, United States
Recruiting
Emory University Children'S Healthcare of Atl
Atlanta, Georgia, United States
Hans Grossniklaus, MD
Recruiting
Ann & Robert H. Lurie Children'S Hospital of Chicago
Chicago, Illinois, United States
Janice Lasky-Zeid, MD
Recruiting
Oregon Health & Science University: Casey Eye Institute
Portland, Oregon, United States
Alison Skalet, M.D., Ph.D
Recruiting
Wills Eye Institute
Philadelphia, Pennsylvania, United States
Carol Shields, MD
Recruiting
St. Jude Children'S Research Hospital
Memphis, Tennessee, United States
Matthew Wilson, MD
Recruiting
Seattle Children'S Hospital; University of Washington
Seattle, Washington, United States
Andrew Stacey, M.D., M.S
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Jan 2017
Primary completion: 31 Dec 2028
Completion: 31 Dec 2030
Last update posted: 22 Apr 2026
Registered enrollment: 800
Registry id: NCT04959097

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.