Clinical trialNCT04981561CompletedPhase 1Interventional

Safety and Tolerability of Zelquistinel in Normal Human Volunteers

SponsorSyndeio Biosciences, IncEnrollment68Major Depressive Disorder

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To evaluate the safety and tolerability of single ascending doses of zelquistinel in normal human volunteers

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Aaron Koenig, MD
Syndeio Biosciences
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

No facility list is in our current data snapshot for this study. The registry record on ClinicalTrials.gov ↗ carries any published locations. Why? →

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboZelquistinel

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 9 Dec 2016
Primary completion: 21 Dec 2017
Completion: 21 Dec 2017
Last update posted: 12 Mar 2026
Registered enrollment: 68
Registry id: NCT04981561

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.