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Clinical trialNCT04984226RecruitingPhase 2Interventional

Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD

SponsorUniversity of California, DavisEnrollment80Chronic Kidney DiseasesDiabetesFatigueInsulin ResistanceMetabolic AcidosisMitochondrial Energetics+1 more conditions
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Skeletal muscle metabolic health is critical for mobility and an underrecognized target of metabolic acidosis in chronic kidney disease. Impaired muscle mitochondrial metabolism underlies poor physical endurance increasing the risk of mobility disability. The proposed project will use precise in vivo tools to study the pathophysiology of poor physical endurance in a clinical trial treating metabolic acidosis among persons living with chronic kidney disease.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

2 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of California Davis Health

    Sacramento, California, United States

    Baback Roshanravan, MD MS
    Recruiting
  • Vanderbilt University Medical Center

    Nashville, Tennessee, United States

    Jorge Gamboa, MD PhD
    Not, yet, recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Sodium bicarbonate →Placebo
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
8 Sept 2023
Primary completion
31 Dec 2026
Completion
31 Dec 2026
Last update posted
6 May 2026
Registered enrollment
80
Registry id
NCT04984226
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.