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Clinical trialNCT05006352CompletedPhase 1Interventional

A Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of DNL343 in Participants With Amyotrophic Lateral Sclerosis

SponsorDenali Therapeutics Inc.Enrollment29Amyotrophic Lateral Sclerosis
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Netherlands
  • Centre for Human Drug Research (chdr)

    Leiden, South Holland, Netherlands

United States
  • Honorhealth

    Scottsdale, Arizona, United States

  • University of California at San Diego

    San Diego, California, United States

  • California Pacific Medical Center

    San Francisco, California, United States

  • Ppd Orlando

    Orlando, Florida, United States

  • Emory University

    Atlanta, Georgia, United States

  • Atrium Health Neurosciences Institute

    Charlotte, North Carolina, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
11 Aug 2021
Primary completion
15 Dec 2022
Completion
5 Jun 2024
Last update posted
19 Sept 2024
Registered enrollment
29
Registry id
NCT05006352

Cross-registrations

EU-CTR / CTIS (EudraCT)2021-001766-37

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.