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Clinical trialNCT05013099UnknownPhase 2Interventional

Study of Zirconium Zr 89 Crefmirlimab Berdoxam PET/CT in Subjects With Advanced or Metastatic Malignancies

SponsorImaginAb, Inc.Enrollment70MelanomaMerkel Cell Carcinoma, UnspecifiedNon Small Cell Lung CancerRenal Cell Carcinoma
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to evaluate whether zirconium Zr 89 crefmirlimab berdoxam (other names 89Zr-crefmirlimab berdoxam, 89Zr-Df-crefmirlimab, 89Zr-Df-IAB22M2C) PET/CT can predict the response of advanced or metastatic melanoma, Merkel cell carcinoma, renal cell carcinoma, or non-small cell lung cancer tumors to immuno-oncology therapy.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

16 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Macquarie University Hospital

    Macquarie Park, New South Wales, Australia

  • Princess Alexandra Hospital

    Woolloongabba, Queensland, Australia

  • Royal Adelaide Hospital

    Adelaide, South Australia, Australia

  • Olivia Newton-John Cancer Research Insititute

    Heidelberg, Victoria, Australia

  • Peter Maccallum Cancer Centre

    Melbourne, Victoria, Australia

Belgium
  • University Hospitals Leuven

    Leuven, Belgium

Netherlands
  • Radboud University Medical Center

    Nijmegen, Gelderland, Netherlands

  • Leiden University Medical Center

    Leiden, Netherlands

Switzerland
  • Lausanne University Hospital

    Lausanne, Switzerland

United Kingdom
  • Northern Centre for Cancer Care and Newcastle University

    Newcastle upon Tyne, United Kingdom

United States
  • Carti Cancer Center

    Little Rock, Arkansas, United States

  • City of Hope

    Duarte, California, United States

  • Providence Saint John'S Cancer Institute

    Santa Monica, California, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, United States

  • Ut Southwestern Medical Center

    Dallas, Texas, United States

  • University of Washington

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Zirconium (89Zr) crefmirlimab berdoxam
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
9 Dec 2021
Primary completion
31 Jul 2025
Completion
31 Jul 2025
Last update posted
22 Jul 2024
Registered enrollment
70
Registry id
NCT05013099

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.